Biological Cycles

Biological Cycles

Current Topics in Cellular Regulation, Vol. 18

1st Edition - July 28, 1981

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  • Editors: Ronald W. Estabrook, Paul Srere
  • eBook ISBN: 9781483217178

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Current Topics in Cellular Regulation, Volume 18: Biological Cycles covers topics on the events of molecular biology, cellular communication, and the merging of cell structure to biochemical function. The book discusses the ornithin-urea cycle; the cycles of glutathione metabolism and transport; and the role of multienzymatic proteins in mammalian pyrimidine biosynthesis. The text also describes the significance of interconvertible enzyme cycles in cellular regulation; regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle; replenishment of citric acid cycle intermediates by the purine nucleotide cycle in rat skeletal muscle. The control of a secondary pathway of ethanol metabolism by differences in redox state; the role of aldolase and fructose bisphosphatase in the control of gluconeogenesis and glycolysis; and the fructose 6-phosphate/fructose 1,6-bisphosphate cycle are also considered. The book further tackles the cycles in polysaccharide biosynthesis and other important biological cycles. Biologists, microbiologists, cellular biologists, and biochemists will find the book invaluable.

Table of Contents

  • List of Contributors and Discussants


    Excerpts From An Interview

    Conference Photographs

    1. The Ornithine-Urea Cycle: Biosynthesis and Regulation of Carbamyl Phosphate Synthetase I and Ornithine Transcarbamylase

    2. On the Cycles of Glutathione Metabolism and Transport

    3. Multienzymatic Proteins in Mammalian Pyrimidine Biosynthesis: Channeling of Intermediates to Avoid Futile Cycles

    4. Interconvertible Enzyme Cycles in Cellular Regulation

    5. Regulation of Mammalian Pyruvate Dehydrogenase Complex by a Phosphorylation-Dephosphorylation Cycle

    6. Phosphorylation-Dephosphorylation Cycles and the Regulation of Fuel Selection in Mammals

    7. Replenishment of Citric Acid Cycle Intermediates by the Purine Nucleotide Cycle in Rat Skeletal Muscle

    8. Control of a Secondary Pathway of Ethanol Metabolism by Differences in Redox State: A Story of the Failure to Arrest the Krebs Cycle for Drunkenness

    9. Aldolase and Fructose Bisphosphatase: Key Enzymes in the Control of Gluconeogenesis and Glycolysis

    10. The Fructose 6-Phosphate/Fructose 1,6-Bisphosphate Cycle

    11. Cycles in Polysaccharide Biosynthesis

    12. Tricarboxylic Acid Cycle Intermediates and the Control of Fatty Acid Synthesis and Ketogenesis

    13. Ferroactivator and the Regulation of Gluconeogenesis

    14. Metabolic Cycles in the Fermentation by Propionic Acid Bacteria

    15. Sterol Structure and Membrane Function

    16. The ATP-Phosphate Cycle

    17. Formation and Utilization of PEP in Microbial Carbohydrate Transport

    18. Cycles in the Function of Mitochondrial Membrane Transport Systems

    19. The Cycling of Oxygen through Intermediates in the Cytochrome Oxidase-Oxygen Reaction

    20. Energy Cycles in Health and Disease

    21. The Glucose-Lactic Acid Cycle and Gluconeogenesis

    22. Amino Acid Cycles in Man

    23. Phosphorylation and Dephosphorylation of Glycogen Phosphorylase: A Prototype for Reversible Covalent Enzyme Modification

    24. Role of Phosphorylation-Dephosphorylation Cycles in the Control of Protein Synthesis in Eukaryotes

    25. Structure and Hormonal Regulation of the Ovalbumin Gene Cluster

    26. Catabolite Repression in Yeast: Mediation by cAMP

    27. Unwinding the Double Helix: Complete Equation for Chemical Equilibrium

    28. The Structure and Evolution of Ribosomes and Their Components

    29. A Cyclic Mechanism for Excitation and Adaptation

    30. Protein Synthesis and Protein Turnover in Circadian Cycles

    31. Membrane Cycling in Secretion: A Morphological Approach

    32. Remarks in Honor of Professor Sir Hans Krebs

    33. Response


    Contents of Previous Volumes

Product details

  • No. of pages: 594
  • Language: English
  • Copyright: © Academic Press 1981
  • Published: July 28, 1981
  • Imprint: Academic Press
  • eBook ISBN: 9781483217178

About the Editors

Ronald W. Estabrook

Paul Srere

Affiliations and Expertise

Veterans Affairs Medical Center, Dallas, Texas, U.S.A.

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