Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health

1st Edition - November 14, 2017

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  • Editors: Suresh Sikka, Wayne Hellstrom
  • eBook ISBN: 9780128013137
  • Hardcover ISBN: 9780128012994

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Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men’s reproductive and sexual health with eight sections designed to enable a logical flow of such knowledge. The book is focused on the biology of key organs involved in male reproduction and the environmental influences affecting their functions with particular emphasis on clinical aspects. Individual chapters within the book range from basic to translational aspects, but all hold clinical relevance. This is an essential reference for those working and learning in the field of human reproduction, reproductive toxicology and environmental influences on reproductive and sexual health.

Key Features

  • Brings together the leading authorities working in the field of male reproduction and sexual health and how the environment affects these issues
  • Provides guidelines and reference values of various reproductive hormones, semen parameters, inclusion/exclusion criteria for clinical trials
  • Discover the most efficient methods by which to design clinical protocols for sperm safety studies and reproductive toxicology trials


Professional researchers in the field of reproductive toxicology, preclinical toxicologists, andrologists, reproductive epidemiologists, endocrinologists and Urologists involved in research, graduate students in toxicology

Table of Contents

  • Part-A Men’s Reproductive Health
    Section I - Biology of Male Reproductive Tract and Environment
    1. How the Environment and Air Pollution Disrupts Spermatogenesis and Male Reproductive Health: A Mechanistic Approach
    2. Environmental Issues Resulting in Hypogonadism
    3. Environmental Risk Factors Related to Male Reproductive Health
    4. Effect of Environmental Toxins on Spermatogonial Stem Cells

    Section II – Life Style Issues and Male Reproductive Health
    5. Lifestyle Stress and its Impact on Male Reproductive Health
    6. The Impact of Lifestyle Factors on Male Reproduction: Body Composition, Diet, Exercise, and Recreational Drug Use
    7. Obesity, Hypogonadism, and Male Fertility – The Role of Diet and Environment
    8. Lifestyle Factors and Medical Therapy in the Management of Male Fertility
    9. Yoga Meditation Lifestyle Intervention: Impact on Male Reproductive Health
    10. Lifestyle, Environment and Male Reproductive Health: A Lesson to Learn

    Section III – Environmental Factors Affecting Male Reproductive Health
    11. Environmental Issues in Maintaining Reproductive Health
    12. Environmental Contamination and Testicular Function
    13. Reproductive Health Issues in Latin America: Role of Environment
    14. Adverse Effects of Drugs on Male Reproduction
    15. Beneficial or Detrimental Effects of PDE5-inhibitors on Semen Quality and Testicular Function?
    16. Environmental Issues Resulting in Hypogonadism i.e., Andropause

    Section IV – Mechanistic Approaches to Environmental Issues
    17. Androgen receptor modulators: The Impact of Environment and Lifestyle Choices on Reproduction
    18. Heavy Metal Toxicity Affecting Fertility and Reproduction of Males
    19. Environmental Toxicants Induced Male Reproductive Toxicity – Role of Oxidative Stress
    20. Role of Environmental Toxicants in Sperm Autophagy, Mitophagy, and Apoptosis
    21. Impact of Environmental Factors on the Genomics and Proteomics Landscapes of Male Infertility
    22. Role of Sperm Chromatin Structure Assay Technology in Evaluating Sperm DNA Damage due to Environmental Influences

    Section V – Laboratory Aspects in the Evaluation of Male Reproductive Function
    23. Standardized Semen Analysis in Multicenter Clinical Trials and Quality Control Management for Reproductive Toxicity Studies

    PART-B Men’s Sexual Health
    Section VI –Biology of Male Sexual Function and Environment
    24. Components of Erection and Ejaculation as the Potential Target Systems for Environmental Toxicants.
    25. Effects of Endocrine Disrupting Chemicals (EDCs) on Penile Tissue Development, Histo-architecture and Erectile Physiology
    26. Penile Fibrogenesis Affecting Men’s Reproductive and Sexual Health: Role of Age and Environmental Factors
    27. The Epidemiology and Pathophysiology of Erectile Dysfunction and the Role of Environment – Current Updates

    Section VII – Environmental Issues Affecting Male Sexual Function
    28. Environment, Drugs, and Chemical Exposures in the Realm of Human Sexuality
    29. Role of Risk Factors Such as Smoking, Alcohol and Substance Abuse on Sexual Health of Brazilian Men
    30. Effects of Electronic Cigarettes on Men’s Reproductive and Sexual Health
    31. The Influences of Diet, Supplements and Environmental Stressors on Male Erectile Function
    32. Endocrine Disruptors in the Environment Affecting Erectile Function

    Section VIII – Regulatory and Other Issues Involving Environment Affecting Overall Male Reproductive Health
    33. Environmental Health Policy Regarding Men’s Reproductive and Sexual Health
    34. Drugs of Abuse: Men’s Reproductive and Sexual Health
    35. Post-traumatic Stress Disorder and its Effects on Men’s Sexual and Reproductive Health
    36. Perfumery, Essential Oils and their Reproductive and Sexual Effects

Product details

  • No. of pages: 636
  • Language: English
  • Copyright: © Academic Press 2017
  • Published: November 14, 2017
  • Imprint: Academic Press
  • eBook ISBN: 9780128013137
  • Hardcover ISBN: 9780128012994

About the Editors

Suresh Sikka

Over 40 years of research and teaching experience in the fields of biochemical pharmacology, male reproductive toxicology, infertility, and sexual dysfunction. Certified High-complexity Clinical Lab Director (HCLD), Clinical Consultant (CC) and Clinical Laboratory Specialist (CLS). Directs CLIA/HCFA-certified Andrology clinical laboratory at Tulane University Medical Center. Started unique standardized semen analysis training program at Tulane Urology for Food and Drug Administration (FDA)-recommended multi-center clinical trials for male reproductive toxicology and sperm-safety studies. Author of almost 200 peer-reviewed manuscripts, more than 450 abstracts, 30 book chapters. Gave many presentations and also invited for grand rounds as well as key note speaker at various national and international scientific and professional meetings. Taught and trained numerous research fellows, urology residents and fellows, medical students, and mentor to 4 PhD graduates. Reviewer of several medical publications, grants, and served on many editorial boards.

Affiliations and Expertise

Professor and Research Director of Urology, Andrology Research and Clinical Labs Director, Adjunct Professor of Pharmacology, Biochemistry and Human Genetics, New Orleans, LA, USA

Wayne Hellstrom

More than 30 years of experience researching male infertility, erectile dysfunction, prosthetic surgery, and testosterone deficiency. Received the Young Andrologist Award by the American Society of Andrology (ASA) Author on nearly 500 peer-reviewed publications, and 100 book chapters. Immediate Past-President of International Society for Sexual Medicine, and member of American Association of Genitourinary Surgeons. Editor of several textbooks, including, “ Male Infertility and Sexual Dysfunction.” Associate editor of Urology (Gold), and on the editorial board for Journal of Urology, Journal of Sexual Medicine and Asian Journal of Andrology.

Affiliations and Expertise

Professor of Urology and Chief, Section of Andrology, School of Medicine, Tulane University Health Sciences Center, New Orleans, LA, USA

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  • SCS Tue Jun 19 2018

    Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health, Sikka & Hellstrom;1st Edition

    Great Reproductive Toxicology Text book with a focus on Bio-environmental Factors and Men's health - probably the first one dealing with both Men's reproductive and sexual health combined together. Recommended for diverse readers interested in acquiring more inside knowledge with mechanisms involved related to these topics.