Biochemistry of the amino acids

Preface to the Second Edition Acknowledgments Contents of Volume I Tables and Figures Metabolism Summary Schemes Chapter VI. Intermediary Metabolism of theamino Acids A. General Considerations B. Alanine C. β-Alanine and β-Aminoisobutyric Acid Biosynthesis Degradation D. Aspartic Acid and Asparagine General Considerations Asparagine Convertion of Aspartate to Fumarate β-Methylaspartic Acid Adenylosuccinic Acid Hydroxyaspartic Acid Synthesis of the Pyrimidine Ring Other Reaction of Aspartic Acid E. Glutamic Acid and Glutamine General Considirations the Mesaconate Pathway Metabolism of L-and D-Glutamic Acids in Animals Glutathione Glutamine Degcarboxylation of Glutamic Acid Synthesis of the Purine Ring F. Glycine, Serine, and Sarcosine Formation and Degradation of Glycine Synthesis of Creatine and Creatinine Porphyrin Synthesis Glycine-Serine Interconversion; Folic Acid Derivatives Biosynthesis of Serine from Carbohydrate Relationships Between Serine, 2-Aminoethanol, Choline, and Sarcosine Degradation of Serine Sphingosine Lombricine and Serine-Aminoethanol Phosphodiester Other Reactions of Glycine and Serine G. Threonine Biosynthesis Degradation Threonine Dehydrases Hydroxyamino Acid Aldolases Conversion of Threonine to Aminoacetone Incorporation of Threonine Carbon into Vitamin B12 H. Arginine, Ornithine, and Citrulline; Urea Synthesis General Considerations Formation of Arginine Formation of Carbamyl Phosphate and Citrulline Alternate Pathways of Urea Formation Other Pathways of Carbamyl Phosphate Formation Arginine Desimidase Canavanine Other Reactions of Arginine and Ornithine I. Proline Biosynthesis of Proline in Microorganisms Biosynthesis of Ornithine in Microorganisms Metabolism in Mammals J. 4-Hydroxyproline General Considerations Conversion of Proline to Collagen Hydroxyproline Degradation K. Valine, Isoleucine, and Leucine Biosynthesis of Valine and Isoleucine Biosynthesis of Leucine Degradation of Leucine Conversion of Leucine to Isoprenoid Compounds Degradation of Valine Degradation of Isoleucine Degradation of Straight-Chain Amino Acids Conversion of Valine, Leucine, and Isoleucine to Other Product L. Methionine and Cysteine General Considerations The Cystathionine Pathway Transmethylation Synthesis of Methionine Other Reactions of Methionine S-Methylcysteine Biosynthesis of Cysteine The Cysteine Desulfhydrase Reaction Desulfuration and Transsulfuration of β-Mercaptopyruvic Acid Alliinase Cysteine and Glutathione Reductases Conversion of Cysteine to Cysteinesulfinic Acid, Taurine, and Related Compounds Thiosulfate Utilization and Formation Other Products of Cysteine Metabolism M. Histidine Biosynthesis Degradative Metabolism The Urocanic Acid Pathway Histamine Other Products of Histidine Metabolism N. Tryptophan Biosynthesis Metabolism General Considerations Conversion to Kynurenine, Nicotinic Acid, and Related Compounds Other Reactions of Kynurenine and Derivatives Metabolism of Anthranilic Acid 5-Hydroxytryptophan and its Metabolites Utilization of Tryptophan for the Formation of Plant Growth Hormone Other Products of Tryptophan Metabolism O. Phenylalanine and Tyrosine Biosynthesis in Microorganisms Metabolic Transformation in Animals Epinephrine and Related Compounds Thyroxine and Related Compounds Melanin Other Reactions of Tyrosine and Phenylalanine P. Lysine Biosynthesis Diaminopimelic Pathway Aminoadipic Acid Pathway Degradation Other Reactions of Lysine Hydroxylysine ReferencesChapter VII. Some Disorders of Amino Acid Metabolism in Man A. Introduction B. Aminoaciduria Introduction Cystinuria Glycinuria Generalized Aminoaciduria Aminoaciduria of the "Overflow" Type C. Excretion of β-Aminoisobutyric Acid D. Disorders of Glycine and Glyoxylate Metabolism Glycinemia Hyperoxaluria E. Phosphoaminoethanol Metabolism Hypophosphatasia F. Metabolism of Ammonia, Arginine, Citrulline, and Ornithine Introduction Argininosuccinic Aciduria Ammonemia Citrullinuria G. Metabolism of Hydroxyproline and Proline Hydroxyprolinemia Prolinemia H. Metabolism of Isoleucine, Leucine, and Valine Maple Syrup Urine Disease Propionate Metabolism I. Methionine Metabolism Cystathioninuria Homocystinuria J. Histidine Metabolism Histidinemia Cerebromacular Degeneration Mastocytosis K. Tryptophan Metabolism Hartnup Diseas Carcinoid L. Phenylalanine and Tyrosine Metabolism Alcaptonuria Excretion of Tyrosine and p-Hydroxyphenylpyruvic Acid Albinism Pheochromocytoma and Neuroblastoma Thyroid Hormones Phenylpyruvic Oligophrenia ReferencesAuthor IndexSubject Index for Volumes I and II