Biochemical Mechanisms of Paraquat Toxicity

Biochemical Mechanisms of Paraquat Toxicity

1st Edition - January 1, 1977

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  • Editor: Anne Pomeroy Autor
  • eBook ISBN: 9780323159074

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Biochemical Mechanisms of Paraquat Toxicity presents the proceedings of the First Iowa Symposium on Toxic Mechanisms that was held from June 28-29, 1976. The symposium brought together a diverse group of investigators consisting of chemists, pharmacologists, pathologists, biochemists, and toxicologists from the United States, Canada, and Europe who have been interested in the mechanism of paraquat toxicity. The book includes papers on the following topics: the general features of toxic lung injury and observations with paraquat and diquat; electron transfer reactions of paraquat; the pathological effects of paraquat on the human lung; and the importance of oxygen and pulmonary alveolar surfactant in lung injury by paraquat. Other papers deal with the effects of paraquat on kidney and liver function in experimental animals; lipid peroxidation as a proposed mechanism for paraquat toxicity; pulmonary fibrosis as a consequence of paraquat toxicity; biochemical changes in lungs exposed to paraquat; effects of selenium deficiency on paraquat toxicity; and treatment for paraquat poisoning.

Table of Contents

  • Contributors and Participants


    Primary Events in Lung Following Exposure to Toxic Chemicals

    Electron Transfer Reactions of Paraquat

    The Pathology of the Lung in Paraquat Poisoning

    Importance of Oxygen and of Pulmonary Alveolar Surfactant in Lung Injury by Paraquat

    The Relevance of Paraquat Accumulation by Tissues

    In Vitro and In Vivo Effects of Paraquat on Rat Liver Mitochondria

    Paraquat Induced Functional Changes in Kidney and Liver

    On the Mechanism of the Potentiation by Beta Adrenergic Agonists of Paraquat Toxicity in Rats and Mice

    Lipid Peroxidation as a Proposed Mechanism for Paraquat Toxicity

    Pulmonary Fibrosis and Paraquat Toxicity

    Biochemical Changes in Lungs Exposed to Paraquat

    Paraquat Toxicity: Effects of Selenium Deficiency and Anti-Inflammatory Drug Pretreatments

    An Effective Treatment for Paraquat Poisoning

    Optical Spectra


Product details

  • No. of pages: 250
  • Language: English
  • Copyright: © Academic Press 1977
  • Published: January 1, 1977
  • Imprint: Academic Press
  • eBook ISBN: 9780323159074

About the Editor

Anne Pomeroy Autor

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