Biochemical Actions of Hormones V1

List of Contributors

Preface


1. Hormonal Responses in Amphibian Metamorphosis

I. Introduction

II. Interrelationships of Hormones during Anuran Metamorphosis

III. Changes in Blood

IV . The Development of the Nervous System

V. Responses of the Skin

VI. Intestinal Development

VII. Regression of the Pancreas

VIII. Developmental Changes in the Liver

IX. Tail Resorption

X. Changes in Calcium and Bone Metabolism

XI. Miscellaneous Effects

XII. Some General Comments and Conclusions about Anuran Metamorphosis

References


2. The Developmental Formation of Enzymes in Rat Liver

I. Introduction

II. Critical Stages of Enzymic Differentiation in the Liver

III. The Late Fetal Stage

IV. Neonatal Period

V. Late Suckling Period

VI. The Problems of the Mechanisms of Developmental Enzyme Formation

VII. Biochemical Differentiation of Liver in Species Other Than Rat

VIII. General Observations

IX. Brief Summary

References


3. Regulation of Protein Synthesis by Growth and Developmental Hormones

I. Introduction

II. Regulatory Mechanisms of Protein Synthesis in Animal Cells

III. Hormones and Protein Synthesis

IV. The Role of Cell Structure

V. Phenomenology and Mechanism of Action

References


4. The Regulation of Some Biochemical Circadian Rhythms

I. Introduction

II. Circadian Rhythms in the Pineal Gland

III. Circadian Rhythm of Hepatic Tyrosine Transaminase Activity

IV. Conclusions: Possible Driving Oscillations of Biochemical Rhythms

References


5. Hormones and Transport across Cell Membranes

I. Introduction

II. Some Hormonal Effects on Transports

III. Evidence that Hormones Affect Only One of the Transport Systems for Neutral Amino Acids

IV. Concluding Remarks

References


6. Binding of Hormones to Serum Proteins

I. General Characteristics of Hormone-Protein Complexes

II. Thyroid Hormone-Binding Proteins

III. Steroid Hormone-Binding Proteins

IV. Synopsis

References


7. Insulin and Protein Synthesis

I. Introduction

II. General Effects of Insulin on Nitrogen Metabolism

III. Protein Synthesis in Muscle

IV. Accumulation of Amino Acids by Muscle

V. Effect of Insulin on Labeling of Aminoacyl-tRNA

VI. Insulin and RNA Metabolism in Muscle

VII. Protein Synthesis in Subcellular Systems

VIII. Summary and Conclusions

References


8. Mineralocorticoids

I. Historical Background

II. Comparative Physiology

III. The Induction Hypothesis

IV. Role of Aldosterone-Induced Protein (AIP) in Mineralocorticoid Action

V. The Oxidative Phosphorylation Hypothesis

VI. Model of the Mechanism of Mineralocorticoid Action

VII. Future Directions

References


9. Parathyroid Hormone and Calcitonin

I. Introduction

II. Calcium Exchange in Cells and Subcellular Compartments

III. Bone Cells and Their Function

IV. Parathyroid Hormone, 3',5'-AMP, and Intracellular Calcium

V. Mode of Action of Calcitonin

VI. PTH, Vitamin D, and Intracellular Ca++

VII. Summary and Conclusions

References


10. Mechanism of Action of Thyrotropin

I. Introduction

II. The Specific Interaction of Thyrotropin with Thyroid Cellular Components

III. Cyclic 3',5'-AMP as the Intracellular Mediator of Thyrotropin Action on the Thyroid

References


11. The Thymus as an Endocrine Gland: Hormones and Their Actions

I. Introduction

II. Modern Concepts of the Thymus as an Endocrine Gland

III. Chemistry and Actions of Thymic Fractions

IV. Biological Effects of Thymic Extracts

V. Summary

References


12. Plant Hormones

I. Introduction

II. Auxins

III. Gibberellins

IV. Cytokinins

V. Abscisic Acid

VI. Ethylene

References

Author Index

Subject Index