Bioceramics and their Clinical Applications

1st Edition

Editors: T Kokubo
Hardcover ISBN: 9781845692049
eBook ISBN: 9781845694227
Imprint: Woodhead Publishing
Published Date: 25th March 2008
Page Count: 784
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Table of Contents

Part 1 Fundamentals of bioceramics: The structure and mechanical properties of bone; Fabrication processes for bioceramics; The microstructure of bioceramics and its analysis; The mechanical properties of bioceramics; The design of ceramics for joint replacement; Cellular response to bioactive ceramics; In vitro evaluation of bone bioactivity; Osteoconduction and its evaluation; Osteoinduction and its evaluation. Part 2 Types of bioceramics: Alumina ceramics; Zirconia ceramics; Bioactive glasses; Bioactive glass-ceramics; Calcium sulphate; Tricalcium phosphate-based ceramics; Hydroxyapatite; Tricalcium phosphate/hydroxyapatite biphasic ceramics; Si-substituted hydroxyapatite; Calcium phosphate cement; Calcium phosphate coatings; Titania-based materials; Ceramic-polymer composites; Dental ceramics; Dental glass-ceramics. Part 3 Clinical applications of bioceramics: Clinical application of bioactive glasses; Clinical application of bioactive glass-ceramics; Clinical application of hydroxyapatite; Clinical applications of alumina ceramics in joint replacement; Clinical applications of ceramics/polyethylene in joint replacement; Tissue engineering using bioceramics.


Bioceramics have been used very successfully within the human body for many years. They are commonly used in orthopaedic surgery and dentistry but they are potentially suitable for a wide range of important applications within the medical device industry. This important book reviews the range of bioceramics, their properties and range of clinical uses.

Chapters in the first section of the book discusses issues of significance to a range of bioceramics such as their structure, mechanical properties and biological interactions. The second part reviews the fabrication, microstructure and properties of specific bioceramics and glasses, concentrating on the most promising materials. These include alumina and zirconia ceramics, bioactive glasses and bioactive glass-ceramics, calcium sulphate, tricalcium phosphate-based ceramics, hydroxyapatite, tricalcium phosphate/hydroxyapatite biphasic ceramics, si-substrated hydroxyapatite, calcium phosphate cement, calcium phosphate coating, titania-based materials, ceramic-polymer composites, dental ceramics and dental glass-ceramics. The final group of chapters reviews the clinical applications of bioceramics in joint replacement, bone grafts, tissue engineering and dentistry.

Bioceramics and their clinical applications is written by leading academics from around the world and it provides an authoritative review of this highly active area of research. This book is a useful resource for biomaterials scientists and engineers, as well as for clinicians and the academic community.

Key Features

  • Provides an authoritative review of this highly active area of research
  • Discusses issues of significance of a range of bioceramics such as their structure, mechanical properties and biological interactions
  • Reviews the clinical applications of bioceramics in joint replacement, bone grafts, tissue engineering and dentistry


Biomaterials scientists and engineers; Clinicians and the academic community


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© Woodhead Publishing 2008
Woodhead Publishing
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About the Editors

T Kokubo Editor

Tadashi Kokubo is a Professor at the College of Life and Health Sciences, Chubu University, Japan. He is a member of many academic institutions in the area of ceramics and biomaterials, including the Japanese Society for Biomaterials, the Ceramic Society of Japan, the International Society for Ceramics in Medicine, and the World Academy of Ceramics.

Affiliations and Expertise

Chubu University, Japan