Basic Medical Endocrinology, 4e provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. Topics are approached from the perspective of a physiologist with over 40 years of teaching experience.
This fourth edition is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. Each of the fourteen chapters starts with an overview of the topic and ends with a Suggested Reading list. Initial chapters lay a foundation by presenting basic information and principles of hormone structure, secretion, and actions, and the physiological roles of the principal endocrine glands. Subsequent chapters address the role of the endocrine system in solving such physiological problems as the regulation of the volume and composition of body fluids in the face of changing environmental demands, and the regulation of short- and long-term energy balance. The final chapters deal with the indispensable role of hormones in growth, development and reproduction.
- Strikes an excellent balance between systems/organismal level of overview and cellular/molecular analysis
- Richly illustrated with over 250 full color figures, descriptive schematic diagrams, and laboratory findings
- All chapters have been thoroughly rewritten and updated, including new discussions of adrenal steroid biosynthesis, the parathyroid in osteoporosis, obesity and metabolism, as well as an entirely new chapter on gastrointestinal hormones
- Editor has 45 years of experience teaching endocrinology and physiology to medical students at Harvard and UMass
Upper division undergraduate and graduate students in biology, physiology, zoology; medical students; researchers and professionals in endocrinology and bone/mineral research.
List of Figures Preface to the Fourth Edition Preface to the First Edition Preface to the Second Edition Preface to the Third Edition Chapter 1 Introduction Biosynthesis of Hormones Storage and Secretion Hormones in Blood Hormone Degradation Mechanisms of Hormone Action Specificity Characteristics of Receptors Hormonal Actions Mediated by Intracellular Receptors Hormonal Actions Mediated by Surface Receptors The G-protein Coupled Receptors Receptors that Signal through Tyrosine Kinase Regulation of Hormone Secretion Negative Feedback Positive Feedback Feed Forward Measurement of Hormones Immunoassays Hormone Levels in Blood Suggested Reading Chapter 2 Pituitary Gland Morphology Physiology of the Anterior Pituitary Gland Glycoprotein Hormones Growth Hormone and Prolactin Adrenocorticotropin Family Development of the Anterior Pituitary Gland Regulation of Anterior Pituitary Function Hypophysiotropic Hormones Thyrotropin Releasing Hormone (TRH) Gonadotropin Releasing Hormone Control of GH Secretion Corticotropin Releasing Hormone Dopamine and control of Prolactin Secretion Secretion and Actions of Hypophysiotropic Hormones Feedback Control of Anterior Pituitary Function Physiology of the Posterior Pituitary Regulation of Posterior Pituitary Function Suggested Reading Chapter 3 Thyroid Gland Morphology Thyroid Hormones Biosynthesis Iodine Trapping Thyroglobulin Synthesis Incorporation of Iodine Hormone Storage Secretion Control of Thyroid Function Effects of Thyroid-Stimulating Hormone Effects of the Thyroid-Stimulating Immunoglobulins Autoregulation of Thyroid Hormon
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- © Academic Press 2009
- 15th August 2008
- Academic Press
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Dr. Goodman has forty-five years of experience teaching endocrinology and physiology to medical students at Harvard Medical School and at the University of Massachusetts Medical School. He has been engaged in NIH funded research in endocrinology for 40 years and published more than 150 articles in leading endocrinology journals. He is the founding Chairman of his department at UMass and has recently retired as Chairman after serving for 36 years..
Department of Physiology, University of Massachusetts Medical School, Worcester, USA