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Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology.
Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.).
- Presents an in-depth overview of skeletal biology, from molecular to organ level
- Offers refresher level content for clinicians or researchers outside their areas of expertise
- Includes updated and complete references
- Incorporates expanded study questions at the end of each chapter for further exploration
- Covers topics relevant to a modern course in skeletal biology
Graduate students, medical fellows/residents, researchers, and academic clinicians in the fields of bone biology, endocrinology, osteology, rheumatology, and dentistry
1. Bone Morphology and Organization
2. Bone Cells
3. Local Regulation of Bone Cell Function
4. Bone Modeling and Remodeling
5. Skeletal Imaging
6. Skeletal Hard Tissue Biomechanics
7. Techniques in Histomorphometry
8. Skeletal Genetics: From Gene Identification to Murine Models of Disease
9. Mechanical Adaptation
10. Fracture Healing
11. Craniofacial Biology, Orthodontics, and Implants
12. Skeletal Growth and Development
13. Calcium and Phosphate: Hormonal Regulation and Metabolism
15. Hormonal Effects on Bone Cells
16. Metabolic Bone Diseases
17. Pharmaceutical Treatments of Osteoporosis
- No. of pages:
- © Academic Press 2019
- 22nd February 2019
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
David B. Burr is a University Distinguished Professor of Anatomy and Cell Biology at Indiana University School of Medicine, and Professor of Biomedical Engineering at IUPUI. He joined the Indiana University School of Medicine faculty in 1990 as Chair of the Department of Anatomy (1990-2010), following faculty positions at the University of Kansas and West Virginia University Medical Schools. He served as President of the American Association of Anatomists (2007-2009) and the Orthopaedic Research Society, and is the Director of the IBMS Sun Valley Workshop on Musculoskeletal Biology. He is a fellow of the American Association of Anatomists, and serves as Editor-in-Chief for Current Osteoporosis Reports, Associate Editor for Bone and the J of Musculoskeletal and Neuronal Interactions. He is the author of more than 230 research articles in the peer- reviewed literature, 48 book chapters and reviews, and four books on the structure, function and mechanics of bone.
Professor, Department of Anatomy and Cell Biology, Indiana University School of Medicine; Professor of Biomedical Engineering (IUPUI), and Professor of Biomedical Engineering (Purdue University); Adjunct Professor of Anthropology, Department of Anthropology, IUPUI and Indiana University, Indianapolis, IN, USA
Matthew R. Allen is an Associate Professor of Anatomy and Cell Biology at Indiana University School of Medicine. His research career, and interest in bone biology, began at Alma College during a summer research fellowship and continued during his years as a PhD student at Texas A&M (in Kinesiology) and post-doctoral fellow at IU School of Medicine. His research focuses on understanding how interventions can be maximized to strengthen the skeleton and his teaching duties include Medical Histology (to first year medical students) and Basic Bone Biology (to graduate students). He serves on the Editorial Board for the Journal of Bone and Mineral Research, BONE, and BoneKEY, and as an Associate Editor for Clinical Reviews in Bone and Mineral Metabolism. He has authored more than 70 research articles and 18 book chapters and reviews.
Assistant Professor, Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, USA
Praise for the First Edition:
"I have enjoyed instructing graduate students and orthopedic residents in bone physiology but a reoccurring frustration has been the lack of a comprehensive textbook. I was delighted to learn that Drs. Burr and Allen were editing a textbook, Basic and Applied Bone Biology, and found the quality of the presentation to actually exceed my high expectations…I look forward to including it in my personal library as well as using it as a textbook!"--Russell T. Turner, PhD, Professor and Director, Skeletal Biology Laboratory, College Of Public Health and Human Sciences, Oregon State University, Oregon, USA
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