This volume is THE definitive, completely up-to-date, reference work for ALL researchers and clinicians working in autoimmunity.

Up-to-Date: This is a timely critical review of more than 100 autoantibodies by leading experts in their respective fields, and includes many recent references.

International Experts: The 120 Chapters have been written by the top international cadre of authors who have provided structured, expert contributions.

Comprehensive: A total comprehensive perspective on the processes which induce, inhibit or otherwise affect autoantibodies in humans.

Useful to Researchers and Clinicians: Chapters generally include methods of detection, pathogenic role, factors in pathogenicity and genetics as well as clinical utility with disease associations and frequencies.

Table of Contents


The Uses of Autoantibodies. Acetylcholine Receptor Autoantibodies. Actin Autoantibodies. Affinity and Avidity of Autoantibodies. Alpha-Galactosyl (ANTI-GAL) Autoantibodies. Aminoacyl-tRNA Histidyl (Jo-1) Synthetase Autoantibodies. Aminoacyl-tRNA (other than Histidyl) Synthetase Autoantibodies. Antineutrophil Cytoplasmic Antibodies in Inflammatory Bowel Diseases. Antineutrophil Cytoplasmic Autoantibodies with Specificity for Myeloperoxidase. Antineutrophil Cytoplasmic Autoantibodies with Specificity for Proteinase 3. Antineutrophil Cytoplasmic Autoantibodies with Specificity other than PR3 and MPO (X-ANCA). Antinuclear Antibodies. Autoantibodies in Therapeutic Preparations of Human IgG (IVIg). Autoantibodies that Penetrate into Living Cells. Autoantibody Subclasses. &bgr;2-Glycoprotein I Autoantibodies. Beta-Adrenergic Receptor (and other hormone receptor) Autoantibodies. Bromelain-treated Erythrocyte Autoantibodies. C1 Inhibitor Autoantibodies. C1q Autoantibodies. Calcium Channel and Related Paraneoplastic Disease Autoantibodies. Calcium Channel Autoantibodies and Amyotrophic Lateral Sclerosis. Centriole and Centrosome Autoantibodies. Centromere Autoantibodies. Chromo Autoantibodies. Coagulation Factor VIII Autoantibodies. Coagulation Factor (excluding Factor VIII) Autoantibodies. Collagen Autoantibodies. Cryoglobulins. Cryoglobulins Secondary to Hepatitis C Virus Infection. Cytokine Autoantibodies. Cytoskeletal Autoantibodies. dsDNA Autoantibodies. Endomysial Autoantibodies. Endothelial Cell Autoantibodies. Fibrillarin Autoantibodies. Fibronectin Autoantibodies. 56-kd Nuclear Protein Autoantibodies. Filaggrin (Keratin) Autoantibodies. Ganglioside Autoantibodies. Gliadin Antibodies. Glomerular Basement Membrane Autoantibodies. Glutamic Acid Decarboxylase Autoantibodies in Diabetes Mellitus. Glutamic Acid Decarboxylase Autoantibodies in Stiff-Man Syndrome. Glycolipid (excluding G


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Elsevier Science
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About the authors

J.B. Peter

Affiliations and Expertise

Specialty Laboratories, Inc., 2211 Michigan Avenue, Santa Monica, CA 90404-3900, USA

Yehuda Shoenfeld

Prof. Yehuda Shoenfeld is the founder and head of the Zabludowicz Center for Autoimmune Diseases, at the Sheba Medical Center which is affiliated to the Sackler Faculty of Medicine in Tel-Aviv University, in Israel. Dr. Shoenfeld is the Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at the Tel-Aviv University. His clinical and scientific works focus on autoimmune and rheumatic diseases, and he has published more than 1750 papers in journals such as New Eng J Med, Nature, Lancet, Proc Nat Acad Scie, J Clin Invest, J Immunol, Blood, FASEB, J Exp Med, Circulation, Cancer and others. His articles have had over 35,000 citations. He has written more than three hundred and fifty chapters in books, and has authored and edited 25 books, some of which became cornerstones in science and clinical practice, such as "The Mosaic of Autoimmunity", "Infections and Autoimmunity" and the textbook "Autoantibodies" and "Diagnostic criteria of autoimmune diseases", all of which were published by Elsevier and sold by the thousands. He is on the editorial board of 43 journals in the field of rheumatology and autoimmunity and is the founder and the editor of the IMAJ (Israel Medical Association Journal) the representative journal of science and medicine in the English language in Israel, and also is the founder and Editor of the "Autoimmunity Reviews" (Elsevier) (Impact factor 7.9) and Co-Editor of "Journal of Autoimmunity" (Impact factor 8.1). He has organized over 20 international congresses in autoimmunity. Prof. Shoenfeld received the EULAR prize in 2005, in Vienna, Austria: "The infectious etiology of anti-phospholipid syndrome". He has received a gold medal from the Slovak Society of Physicians for his contribution to Israel – Slovakia collaboration (March 2006), and is honorary member of the Hungarian Association of Rheumatology. In UC Davis, USA, Dr. Shoenfeld received the Nelson's Prize for Humanity and Science for 2008. In 2009 he was honore

Affiliations and Expertise

Zabludowicz Center for Autoimmune Diseases,Sheba Medical Center, Affiliate of Tel-Aviv University, Israel