COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
Atmospheric Oxidation and Antioxidants - 1st Edition - ISBN: 9780444896179, 9780444597038

Atmospheric Oxidation and Antioxidants, Volume III

1st Edition

0.0 star rating Write a review
Author: Bozzano Luisa
eBook ISBN: 9780444597038
Imprint: Elsevier Science
Published Date: 10th May 1993
Sales tax will be calculated at check-out Price includes VAT/GST
Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Table of Contents

1. Lipid Peroxidation and its Inhibition (E. Niki). Introduction. Lipids in Biomembranes. Peroxidations of Lipids in the Membranes. Inhibition of Lipid Peroxidation. Epilogue. 2. Electron Spin Resonance and Spin Trapping (P.J. Thornalley). Electron Spin Resonance of Free Radical Intermediates in Biological Oxidations. Electron Spin Resonance: Theoretical Principles. Practical Aspects of Electron Spin Resonance of Biological Systems. The ESR Technique of Spin Trapping. Free Radical Intermediates in Biological Oxidations: Classification of Biological Oxidation Mechanisms. Electron Spin Resonance Studies of Free Radicals in Biological Oxidations. Conclusions. 3. Transition Metal Ions and Antioxidant Proteins in Extracellular Fluids (J.M. Gutteridge, B. Halliwell). Oxygen Toxicity. Biological Antioxidants. Protein Antioxidants of Extracellular Fluids. Summary. 4. Sensitization and Protection of Oxidative Damage Caused by High Energy Radiation (P. Wardman). Introduction. Quantitation of Radiation Damage. Targets in Radiobiology: The Focus of Oxidative Stress. The Oxygen Effect in Radiobiology. Oxygen-Mimetic Compounds. Antioxidants as Radiation Protectors. Clinical Exploitation of Radiation Sensitization and Protection. The Oxygen Paradox: Is it a Sensitizer or a Protector? Conclusions. 5. Interactions of Melanin with Oxygen (and Related Species) (T. Sarna, H.M. Swartz). Summary. Introduction. Redox Properties of Melanin Relevant to its Interactions with Oxygen. Oxidation of Monomeric Precursors of Melanin. Interaction of Melanin with Ground State Molecular Oxygen. The Ability of Melanin to Quench and Induce Reactive Species Derived from Oxygen. Oxygen-Dependent Photoreactions of Melanin. Degradative Oxidation of Melanin in the Dark. Appendix. 6. Oxidation of Tetrahydrofolates and Tetrahydrobiopterin by Molecular Oxygen (J.A. Blair, G. Farrar). Introduction. Tetrahydrofolate (VI). 5-Methyltetrahydrofolate (III). 10-Formyltetrahydrofolate (V). Polyglutamates. Tetrahydrobiopterin (VII). Biological Implications. 7. Prostaglandin Synthesis and Co-oxidation: Prostaglandin H Synthase-Linked Radical Reactions (G.A. Reed). Introduction. The Arachidonic Acid Cascade. Prostaglandin H Synthase: The Cyclooxygenase Reaction. Prostaglandin H Synthase: Classical Peroxidase Reactions. Non-Classical Peroxidative Oxidations. Commentary. 8. Antioxidants in Vitro and in Vivo (G. Scott). Introduction. Oxidation in Vitro and in Vivo. Mechanisms of Antioxidant Action. 9. Mechanisms of Antioxidant Action in Living Organisms (D.G. Pobedimskij, E.B. Burlakova). Introduction. Mechanisms of Antioxidant Effects on Cell Metabolism. Antioxidants and Their Use in the Biotechnology of Protein Preparations and Biologically Active Substances. Conclusion. 10. Antioxidant Role of Vitamin E (H.H. Draper). Introduction. Lipid Peroxidation. Ozone and Lipid Peroxidation. Nitrogen Dioxide and Lipid Peroxidation. The Dietary Selenium - Vitamin E Interrelationship. Atmospheric Oxidants and their Vitamin E Requirement. 11. Medical Aspects and Techniques for Peroxidases and Catalases (D. Metodiewa, H.B. Dunford). Abbreviations. Introduction. Peroxidases. Catalase. Prostaglandin H Synthase (PGHS). Hydrogen Peroxide. Free Radical Metabolites. Techniques for Medical Use of Catalase and Peroxidase as Therapeutic Agents. 12. Antioxidants and Oncogenesis: Roles in Cancer Causation and Prevention (T.W. Kensler, N.E. Davidson, K.Z. Guyton). Summary. Introduction. Cancer Chemoprotection by Antioxidants. Carcinogenicity of Antioxidants. Subject Index.


Volume III addresses our present understanding of how oxidation is involved both positively and negatively in life processes. This is a more recent and rapidly developing aspect of oxidation chemistry and many of the concepts still have to be proved by rigorous scientific investigation. Nevertheless, the mechanistic principles developed as a result of studies in vitro over the years now provide the basis for understanding the complex oxidation chemistry of life processes and its control by biological antioxidants.


© Elsevier Science 1993
10th May 1993
Elsevier Science
eBook ISBN:

Ratings and Reviews

About the Author

Bozzano Luisa