Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging

Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging provides a complete review of computer methods for atherosclerotic plaque reconstruction and characterization. The authors, with their expertise from biomedical engineering, computer science, and cardiology, offer a holistic view. The focus of the book is on the presentation of major imaging techniques, including their limitations. It includes details on the mechanical characterization and properties of plaques and appropriate constitutive models to describe the mechanical behavior of plaques.

The authors explore the challenges of using multiple coronary imaging technologies, and provide the pros and cons of invasive vs. non-invasive techniques. Methods for plaque characterization and 3D reconstruction of coronary arteries using IVUS, OCT, and CT images are described.

This book will help readers study new trends in image processing analysis and plaque characterization, implement automated plaque characterization methodologies, understand coronary imaging drawbacks, and comprehend 3 dimensional coronary artery and plaque reconstruction methods.

• Describes the multimodality imaging techniques that are commonly used in the diagnosis of arterial diseases, including intravascular ultrasound, optical coherence tomography, angiography, computed tomography angiography, and magnetic resonance angiography
• Discusses in-depth the computational methods which can be used for the detection of different plaque types
• Explores plaque in 3D reconstruction methods and plaque modeling approaches

Biomedical Engineers, Computer Scientists, Clinicians, Cardiologists

Chapter 1: Introduction

1.1 Anatomy and Physiology of the Cardiovascular System

1.2 Atherosclerosis

1.3 Imaging of Atherosclerosis: Invasive and Non-invasive Techniques

2.1 Coronary Angiography

2.2 Intravascular ultrasound - IVUS

2.3 Optical coherence tomography - OCT

2.4 Computed Tomography - CT

3.1 Two Dimensional (2D) Coronary Quantitative Angiography

3.2 Three Dimensional (3D) Coronary Angiography

3.3　Functionality of 　Three Dimensional (3D) 　Reconstruction: Fractional　Flow Reserve Calculation (FFR)

4.1 Plaque Segmentation

4.2 Plaque Characterization

5.1 Plaque Segmentation Methods using OCT

5.2 Plaque Characterization 　using OCT

5.3 Plaque Characterization

5.4　Plaque characterization and plaque phenotype

6.1 Lumen detection methods

6.2 Plaque detection methods

6.3 CTA segmentation

6.4 3D Artery and 3D CP reconstruction

6.5 Can CTA plaque characterization accuracy be affected?

7.1　Methods 　for 　Three 　Dimensional 　(3D) 　reconstruction 　of 　Coronary　Arteries based on a single intravascular imaging modality

7.2 　Methods 　for 　Three 　Dimensional 　(3D) 　reconstruction 　of 　Coronary　Arteries based on the fusion of intravascular imaging modalities

7.3 Intravascular 3D reconstruction tools

8.1 Imaging Systems and Segmentation Errors

8.2 Fundamental statistics for propagating the error

8.3 Error propagation in plaque characterization

9.1 Micro-CT　vs　Histology

9.2 Image Registration Methods in Medical Imaging

9.3 Inflating Deformed Vessel Images

10.1 Mechanical Plaque Characterization

10.2 Plaque Development Models

10.3　Prognosis of Atherosclerosis

11.1 Towards novel imaging modalities

11.2 Hybrid Imaging