Assessing Ecological Risks of Biotechnology

Assessing Ecological Risks of Biotechnology

1st Edition - November 8, 1990

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  • Editor: Lev R. Ginzburg
  • eBook ISBN: 9781483289489

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Description

Assessing Ecological Risks of Biotechnology presents a comprehensive analysis of ecological risk assessment for biotechnology as viewed predominantly by scientists doing research in this area, but also by regulators, philosophers, and research managers. The emphasis is on the ecological risks associated with the release of genetically engineered organisms into the environment. The book contains 17 chapters that are organized into four parts. Part I discusses the ecological experience gained from previous biological introductions. Part II explores the ecology and the genetics of microbial communities. Emphasis is given to the transport of microorganisms since one of the major ecological concerns about biotechnology is the danger of the spread of genetically engineered organisms to ecosystems other than the one to which they are released. Part III reviews mathematical models that can be used for ecological risk assessment at four different levels. Part IV concerns the regulation of biotechnology, current research trends, and social values.

Table of Contents


  • Preface

    Part I. Experience with Introduced Organisms

    1. Keystone Species and Community Effects of Biological Introductions

    1.1 Quantitative Estimates

    1.2 Determinants of Major Ecological Effects

    1.3 Species that Constitute New Habitats

    1.4 Species that Modify Existing Habitat

    1.5 Keystone Species that Do Not Initially Change Habitats

    1.6 Synergisms and Invasions by Entire Communities

    1.7 Conclusions

    References

    2. Planned Introductions in Biological Control

    2.1 Classical Biological Control

    2.2 Environmental Impact of Introduced Biological-Control Agents

    2.3 Concluding Remarks

    References

    Part II. Ecology and Genetics of Microbial Populations

    3. Surface Transport of Microorganisms by Water

    3.1 Role of the Application Form

    3.2 Runoff Effects

    3.3 Microorganism-Release Characteristics

    3.4 Case Studies

    3.5 Buffer Areas and Vegetative Filters

    3.6 Modeling Microorganism Movement

    3.7 Summary

    References

    4. Soil and Groundwater Transport of Microoganisms

    4.1 Overview of Issues Relating to the Survival of GEMs

    4.2 Transport of Microorganisms in Soil and Subsurface Environments

    4.3 Summary

    References

    5. Aerial Dispersal of Bacteria

    5.1 Sources and Take-off

    5.2 Aerial Transport

    5.3 Deposition

    5.4 Fate of Deposited Bacteria

    5.5 The Overall Process

    References

    6. Factors Affecting the Transfer of Genetic Information Among Microorganisms in Soil

    6.1 The Soil Ecosystem

    6.2 Microbial Interactions

    6.3 Monitoring GEMs in Soil

    6.4 Gene Transfer in Soil

    6.5 Effects of Physicochemical Factors of Soil on Gene Transfer

    6.6 Conclusions

    References

    7. Genetic Exchange and Genetic Stability in Bacterial Populations

    7.1 Sexuality in Bacteria

    7.2 The Possibility of Genetic Exchange Between Species

    7.3 Interspecific Gene Transfer and Its Consequences

    7.4 Conclusions

    References

    Part III. Mathematical Models in Biotechnology Risk Assessment

    8. Models for the Population Dynamics of Transposable Elements in Bacteria

    8.1 Background and Terminology

    8.2 Models

    8.3 Conclusions

    References

    9. Quantifying Fitness and Gene Stability in Microorganisms

    9.1 General Principles

    9.2 Methodological Issues

    9.3 Specific Methods for Estimating Parameters

    9.4 Caveats and Assumptions

    9.5 Summary and Conclusions

    References

    10. Quantifying the Risks of Invasion by Genetically Engineered Organisms

    10.1 Risk Assessment Using Extreme Value Distribution

    10.2 Discussion

    References

    11. Quantifying the Spread of Recombinant Genes and Organisms

    11.1 Review of Spread Models

    11.2 Using Field Data to Simulate Short-Term Spread

    11.3 Some General Lessons from Existing Theory on Spread

    11.4 The Nature of the Data Available from Field Releases

    11.5 Final Remarks

    References

    Part IV. Regulation, Research Trends, and Social Values

    12. Regulation of Biotechnology by the Environmental Protection Agency

    12.1 Background

    12.2 Statutory Arguments

    12.3 Specific EPA Changes for Regulating Biotechnology

    12.4 Regulatory Considerations for the Future

    12.5 Conclusions

    References

    13. Ecological Considerations in EPA's Review for Field Tests of Genetically Engineered Organisms

    13.1 Regulation by the Office of Pesticide Programs (OPP)

    13.2 Regulation by the Office of Toxic Substances (OTS)

    13.3 Case Studies of 12 Applications

    13.4 Evaluation of the Case Studies

    13.5 Emphasis on Ecological Considerations by the EPA

    14. Regulation and Oversight of Biotechnological Applications for Agriculture and Forestry

    14.1 Present Organizational Structures and Coordination

    14.2 Historical Perspective on Research Guidelines

    14.3 Development of USD A Research Guidelines

    14.4 USDA Regulations for Biotechnology

    14.5 Summary

    References

    15. Ecological Risk Assessment and European Community Biotechnology Regulation

    15.1 Approaches to Regulation in European Countries

    15.2 Toward Community-Wide Regulation

    15.3 Involvement of the EC in the Regulation of Biotechnology

    15.4 A Framework for the Regulation of Biotechnology

    15.5 Regulation of Deliberate Releases

    15.6 Conclusions and Recommendations

    References

    16. Ecological Risk Analysis of Biotechnological Waste Decontamination

    16.1 Applications of Biotechnology to Waste Treatment

    16.2 The Need to Identify and Assess Environmental Risks

    16.3 Scientific Issues

    16.4 EPRI's Risk Analysis Research Strategy

    16.5 Conclusion

    References

    17. On Making Nature Safe for Biotechnology

    17.1 The Effects of Domesticated Species

    17.2 The Effects of Biotechnology on Wild and Natural Ecosystems

    17.3 New Fish for Old

    17.4 Biotechnology and the Return of Land to Nature

    17.5 Ecological Science and the Fate of Nature

    17.6 The Policy Issues

    17.7 Another View of Risk

    References

    Index


Product details

  • No. of pages: 432
  • Language: English
  • Copyright: © Butterworth-Heinemann 1990
  • Published: November 8, 1990
  • Imprint: Butterworth-Heinemann
  • eBook ISBN: 9781483289489

About the Editor

Lev R. Ginzburg

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