The authoritative articles in this book represent the state-of-the-art in arsenic research. Arsenic experts from around the world - participants in the Fifth International Conference on Arsenic Exposure and Health Effects organized by the Society for Environmental Geochemistry and Health in 2002 - present their critical findings. The authors share their latest arsenic research findings in Occurrence, Epidemiology, Biomarkers and Animal Models, Mode of Action, Mode of Action, Risk Estimation, Intervention and Medical Treatment, and Water Treatment and Remediation.
As in past conferences, the first report of elevated arsenic exposures in a new country was given. The Conference introduced the finding of arsenic contamination in Nepal and updates of the arsenic problems in Bangladesh, India, Vietnam are included.
A vital contribution to arsenic study and policy making, this volume examines the global impact of the toxin and discusses arsenic in the environment, mechanisms of arsenic metabolism and carcinogenesis, water treatment technology, and medical care. Arsenic Exposure and Health Effects V offers informed, challenging insights into a highly important and controversial topic.
Occurrence & Exposure. Groundwater arsenic exposure in India (D. Chakraborti, M.K. Sengupta et al.). Groundwater arsenic contamination in Nepal: A new challenge for water supply sector (R.R. Shrestha, M.P. Shrestha et al.). Environmental impacts, exposure assessment and health effects related to arsenic emissions from a coal-fired power plant in central Slovakia; the EXPASCAN study (I. Thornton, M.E. Farago et al.). Trivalent arsenic species: Analysis, stability, and interaction with a protein (G. Jiang, X. Lu et al.). Arsenic in Yellowknife, North West Territories, Canada (W.R. Cullen, E. Polishchuk et al.). Occurrence of public health and environmental hazards and potential remediation of arsenic-containing soils, sediments, surface water and groundwater at the Lava Cap Mine NPL Superfund Site in Nevada County, CA (G.F. Lee, A. Jones-Lee). Investigation of arsenic release from sediment materials to water phases (Tran Hong Con, Nguyen Thi Hanh et al.). Arsenic and heavy metal contamination of rice, pulses and vegetables grown in Samta village, Bangladesh (M.G.M. Alam, E.T. Snow, A. Tanaka). Epidemiology. Criteria for case definition of arsenicosis (D.N.G. Mazumder). Arsenic exposure alters purine metabolism in rats, mice, and humans (L.M. Del Razo, E.A. García-Montalvo, O.L. Valenzuela). Risk analysis of non-melanoma skin cancer incidence in arsenic exposed population (V. Bencko, J. Rameš et al.). Effect of arsenic-contaminated drinking water on skin cancer prevalence in Wisconsin's Fox River Valley (L. Knobeloch, H. Anderson). Biomarkers and Animal Models. Alteration of GSH level, gene expression and cell transformation in NIH3T3 cells by chronic exposure to low dose of arsenic (Yu Hu, Ximei Jin et al.). Laboratory and field evaluation of potential arsenic exposure from mine tailings to grazing cattle (J.C. Ng, S.L. Bruce, B.N. Nollerj). Does arsenic require a carcinogenic partner? (T.G. Rossman, A.N. Uddin et al.). Carcinogenicity of dimethylarsinic acid and relevant mechanisms (M. Wei, H. Wanibuchi et al.). Mode of Action. Enzymology and toxicology of inorganic arsenic (H.V. Aposhian, R.A. Zakharyan et al.). Structural proteomics of arsenic transport and detoxification (Z. Liu, R. Mukhopadhyay et al.). A novel S-adenosylmethionine-dependent methyltransferase from rat liver cytosol catalyzes the formation of methylated arsenicals (S.B. Waters, S. Lin et al.). Metabolism of arsenic and gene transcription regulation: Mechanism of AP-1 activation by methylated trivalent arsenicals (Z. Drobná, I. Jaspers, M. Stýblo). Effect of antioxidants on the papilloma response and liver glutathione modulation mediated by arsenic in Tg.AC transgenic mice (K. Trouba, A. Nyska et al.). Application of filter arrays in the study of arsenic toxicity and carcinogenesis (Jie Liu, Hua Chen et al.). Regulation of redox and DNA repair genes by arsenic: Low dose protection against oxidative stress? (E.T. Snow, Yu Hu et al.). Carcinogenicity of dimethylarsinic acid (DMA) (S.M. Cohen, C. Le et al.). Urinary speciation of sodium arsenate in folate receptor knockout mice (O. Spiegelstein, X. Lu et al.). Some chemical properties underlying arsenic's biological activity (K.T. Kitchin, K. Wallace, P. Andrewes). Arsenic metabolism in hyperbilirubinemic rats: distribution and excretion in relation to transformation (K.T. Suzuki, T. Tomita et al.). Incorporating mechanistic insights in a Pbpk model for arsenic (E.M. Kenyon, M.F. Hughes et al.). Intervention and Medical Treatment. Natural history following arsenic exposure: A study in an arsenic endemic area of West Bengal, India (D.N.G. Mazumder, N. Ghose et al.). Saha's grading of ARSENICOSIS progression and treatment (K.C. Saha). UNICEF and arsenic mitigation a report of the third phase work in Bangladesh (C. Davis). Normative role of WHO in mitigating health impacts of chronic arsenic exposure in the South-east Asia Region (D. Caussy). Only painting tubewells red or green, does not help arsenicosis patients (Q. Quamruzzaman, M. Rahman et al.). Water Treatment and Remediation. "Arsenic Solutions" web platform of >50 options for developing countries: Collaborative design and innovation for the common good (S. Murcott). Investigation of arsenic removing technologies for drinking water in Vietnam (Pham Hung Viet, Tran Hong Con et al.). Removing arsenic from drinking water: A brief review of some lessons learned and gaps arised in Chilean water utilities (A.M. Sancha). Disposal of wastes resulting from arsenic removal processes (M.J. MacPhee, J.T. Novak, R.N. Mutter). Development of a low-waste technology for arsenic removal from water (J. Hlavay, K. Polyák et al.). An Overview of some US EPA and Niehs Programs on Arsenic. An update on some arsenic programs at the US EPA (C.O. Abernathy, M. Beringer et al.).
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- © Elsevier Science 2003
- 18th December 2003
- Elsevier Science
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University of Colorado, Denver, CO, USA
Office of Drinking Water, US Environmental Protection Agency, Washington, DC, USA
US Environmental Protection Agency, Research Triangle Park, NC, USA