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Intracranial arachnoid cysts are congenital malformations with a predilection for the middle cranial fossa and an estimated prevalence in the general population as high as 1.7%. The common assumption is that these cysts are incidental findings and the symptoms associated with them are not caused by the cyst and consequently, that surgical intervention will not benefit the patient. However, there is now a growing understanding reflected in the international literature among neurologists and neurosurgeons that arachnoid cysts do harm and that the patients’ complaints can be relieved by surgical treatment.
Arachnoid Cysts: Epidemiology, Biology, and Neuroimaging gives a broad and updated presentation of the condition, including epidemiology, etiology, biology (including genetics and molecular biology), and neuroimaging of same. This book is written for researchers, residents, and clinical practitioners in clinical neuroscience, neurology, neurosurgery, neuroradiology, and pediatrics.
- Gives a detailed account of all pathophysiological aspects of arachnoid cysts
- Covers epidemiology, etiology, biology, genetics and molecular biology and neuroimaging of arachnoid cysts
- Discusses present controversies in cyst management in a historical perspective
- Provides information of use to researchers, residents, and clinical practitioners in clinical neuroscience, neurology, neurosurgery, neuroradiology, and pediatrics
Researchers, clinical practitioners, and residents in clinical neuroscience, neurology, neurosurgery, and neuroradiology
1. Historical perspective and controversial aspects.
2. Arachnoid cysts - intracranial locations, gender, and sidedness
3. Molecular biology and genetics
4. Arachnoid cysts in glutaric aciduria type I (GA-I)
5. Ultrastructure of arachnoid cysts
6. Pathophysiology of intracranial arachnoid cysts: Hypoperfusion of adjacent cortex
7. Biochemistry – compostion of and possible mechanisms for production of arachnoid cyst fluid
8. The ‘Valve Mechanism’
Prevalence and natural history of arachnoid cysts
9. The prevalence of intracranial arachnoid cysts
10. Classification and location of arachnoid cysts
11. Growth and disappearance of arachnoid cysts
12. Arachnoid cysts and subdural and intracystic haematomas
13. Hydrocephalus associated with arachnoid cysts
14. Radiological work-up, CT, MRI
15. Arachnoid cyst. Prenatal detection, management and perinatal outcome
16. SPECT studies in patients with arachnoid cysts
- No. of pages:
- © Academic Press 2017
- 27th September 2017
- Academic Press
- Paperback ISBN:
- eBook ISBN:
Dr. Wester is a Professor Emeritus in the Departments of Clinical Medicine and Surgical Sciences at the University of Bergen, and the Department of Neurosurgery at Haukeland University Hospital in Bergen, Norway.
Professor Emeritus, Department of Clinical Medicine, Department of Surgical Sciences, University of Bergen and Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway
"Both existing evidence and opposing views, when evidence is not available, are presented. As Knut Wester reflects, this inevitably sometimes results in conflicting information, but these are the prerequisites for giving the full picture to the reader. The book is thus a comprehensive work not only of great importance to people with a particular interest in arachnoid cysts but also of significant practical value to all neurosurgeons by providing guidance for clinical decisions." --Acta Neurochirugica
"In conclusion, the Editor has done an excellent effort in organizing a somewhat confusing field into an organic description and in stimulating a debate in order to oppose a widely diffuse attitude in favor of a more active management of arachnoid cysts. He and his contributing authors should be praised for having eliminated from the discussion old believes [sic] and introduced new information for the debate. Surely, this unique and waited a long time book [sic] has all the qualities to stimulate such a wide interest." --Child's Nervous System
"The Editor has done an excellent effort in organizing a somewhat confusing field into an organic description and in stimulating a debate in order to oppose a widely diffuse attitude in favor of a more active management of arachnoid cysts. He and his contributing authors should be praised for having eliminated from the discussion old believes and introduced new information for the debate…The book is addressed to researchers, clinical practitioners in neurosciences, neurosurgeons and residents, neuroradiologists, pediatricians… and, we could add, psychologists, psychiatrists, epileptologists, and so on. Indeed, only the combined investigation of many specialists could result in a better understanding of these quite complex lesions. Surely, this unique and waited a long time book has all the qualities to stimulate such a wide interest." --Child’s Nervous System, April 2018, Volume 34, Issue 4
"The Norwegian neurosurgeon Knut Wester is internationally recognized for dedicating a large part of his long clinical and academic career to the treatment and study of arachnoid cysts…The first volume (Epidemiology, biology, and neuroimaging) discusses pathology and pathophysiology, and although these themes cannot be separated from knowledgeable neurosurgical management, the purpose of this volume is descriptive understanding not directly aimed at clinical practice. This volume thus contains chapters on biology, theories on physiological mechanisms, epidemiology, and natural history…The second volume (Clinical and surgical management) is collected with the purpose of providing information related to clinical practice with chapters on symptoms, diagnosis, surgical techniques, and outcomes. The last four chapters focus on pediatric, spinal, and sport-related aspects of arachnoid cysts. More than 40 authors from several countries have contributed to the book, most of whom have a significant track record with publications about arachnoid cysts. Knut Wester’s vast knowledge about all aspects of arachnoid cysts is a goldmine for sharing, and accordingly, he is also a major contributor to several chapters…The book is thus a comprehensive work not only of great importance to people with a particular interest in arachnoid cysts but also of significant practical value to all neurosurgeons by providing guidance for clinical decisions." --Marianne Juhler, Acta Neurochirurgica, August 2018, Volume 160, Issue 8
“Overall, these 2 volumes present a comprehensive review of the literature concerning all biological and clinical aspects of ACs, as well as new information such as pearls from Dr. Wester’s extensive personal experience dealing with the surgical treatment of this condition. This book is a valuable addition to the shelf of any neurosurgeon to enhance one’s knowledge of the biology underlying these structures, stimulate interest in this condition, and offer a unique perspective on the effectiveness of surgical treatment for ACs.” -Allyson Alexander, World Neurosurgery, 2019-05-01, Volume 125, page 352
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