Applications of Polyurethanes in Medical Devices

Applications of Polyurethanes in Medical Devices

1st Edition - May 19, 2022

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  • Author: Ajay Padsalgikar
  • Hardcover ISBN: 9780128196731
  • eBook ISBN: 9780128231685

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Applications of Polyurethanes in Medical Devices provides detailed coverage of polyurethane (PU) chemistry, processing and preparation for performant medical devices. Polyurethanes have found many uses in medical applications, due to their biocompatibility, biostability, physical properties, surface polarity, and the ability to suit the field of application. This book enables the reader to understand polyurethane and how this valuable material can be used in medical devices. Sections cover the chemistry, structure, and properties of polyurethane, with in-depth sections examining raw materials, reaction chemistry, synthesis techniques, reaction kinetics, material microstructure, and structure-property relationships. Subsequent chapters demonstrate how polyurethane can be utilized in medical device applications, examining biological properties, rheology and processing before methodical coverage explains how polyurethane may be used for each category of medical device. Finally, future directions, and safety and environmental aspects, are covered.

Key Features

  • Bridges the gap between polyurethane chemistry, processing and preparation for cutting-edge medical device applications
  • Includes in-depth coverage of polyurethane, covering raw materials, chemistry, synthesis techniques, reaction kinetics, properties and microstructural analysis
  • Takes a valuable and practical approach, addressing manufacturing issues and using testing and modeling to solve problems encountered in processing


Plastics engineers, processors, and manufacturers of polyurethanes; medical device manufacturers. Researchers and advanced students in polyurethanes, polymer science, plastics processing, and materials for medical devices

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Dedication
  • Preface
  • 1. An Introduction to Polyurethanes and Medical Devices
  • Abstract
  • 1.1 Polymers
  • 1.2 Medical Devices
  • 1.3 Polyurethanes as Biomaterials
  • References
  • 2. Chemistry of Polyurethane Materials
  • Abstract
  • 2.1 Introduction
  • 2.2 History and Development of Polyurethanes
  • 2.3 Polyurethane Raw Materials
  • 2.4 Polyurethane Reaction Chemistry
  • 2.5 Manufacture of Polyurethanes
  • References
  • 3. Structure and Properties of Polyurethanes
  • Abstract
  • 3.1 Introduction
  • 3.2 Microstructure of Polyurethanes
  • 3.3 Physical Characterization of Polyurethanes
  • 3.4 Morphological Characterization of Polyurethanes
  • 3.5 Molecular Characterization of Polyurethanes
  • References
  • 4. Biological Properties of Polyurethanes
  • Abstract
  • 4.1 Introduction
  • 4.2 Biocompatibility
  • 4.3 Foreign Body Reaction
  • 4.4 Biological Degradation
  • 4.5 Testing Techniques to Evaluate Biostability
  • 4.6 Sterilization
  • References
  • Further Reading
  • 5. Rheology and Processing of Polyurethanes
  • Abstract
  • 5.1 Rheology of Polymer Fluids
  • 5.2 Polyurethane Rheology
  • 5.3 Processing of Polyurethanes
  • 5.4 Polyurethane Scaffolds
  • 5.5 Radiopacity in Polyurethane Formulations
  • References
  • 6. Medical Applications of Polyurethanes
  • Abstract
  • 6.1 Introduction
  • 6.2 Cardiovascular Devices
  • 6.3 Orthopedic Devices
  • 6.4 Neurological Devices
  • 6.5 Polyurethane Applications in Other Systems
  • References
  • Further reading
  • 7. Emerging Developments in Polyurethane Technology
  • Abstract
  • 7.1 Drug Delivery Applications of Polyurethanes
  • 7.2 Surface Modification
  • 7.3 Biodegradable Polyurethanes
  • 7.4 Polyurethane Nanocomposites
  • References
  • 8. Safety, Health and Environmental Issues in Polyurethanes
  • Abstract
  • 8.1 Raw Materials in Polyurethanes
  • 8.2 Sustainable Polyurethanes
  • References
  • Index

Product details

  • No. of pages: 282
  • Language: English
  • Copyright: © William Andrew 2022
  • Published: May 19, 2022
  • Imprint: William Andrew
  • Hardcover ISBN: 9780128196731
  • eBook ISBN: 9780128231685

About the Author

Ajay Padsalgikar

Ajay has a Ph.D. in polymer science from Clemson University, SC. He has spent the last 25 years working in the field of plastics and polyurethanes, 20 of which have been in the field of medical plastics. He has extensive experience in the application of polymers in the manufacture of medical devices. As a Chief Scientific Officer at AorTech Biomaterials, Ajay worked with various medical device manufacturers within different areas of the medical space getting a first-hand feel of the devices and the important properties of polyurethanes necessary in order to fulfil the requirements of the application. Ajay then worked as a Senior Principal Scientist at Abbott, one of world’s leading companies in the manufacture of cardiovascular devices. Currently Ajay serves as a Senior Principal Scientist at DSM within its Biomedical wing. DSM Biomedical is a leading supplier of biomaterials to all the major medical device manufacturers.

Affiliations and Expertise

Senior Principle Scientist, DSM, Exton, PA USA

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