Appetite and Body Weight - 1st Edition - ISBN: 9780123706331, 9780080466460

Appetite and Body Weight

1st Edition

Integrative Systems and the Development of Anti-Obesity Drugs

Editors: Tim Kirkham Steven Cooper
Hardcover ISBN: 9780123706331
eBook ISBN: 9780080466460
Imprint: Academic Press
Published Date: 11th December 2006
Page Count: 384
Tax/VAT will be calculated at check-out
142.00
86.00
107.00
131.00
Unavailable
Compatible Not compatible
VitalSource PC, Mac, iPhone & iPad Amazon Kindle eReader
ePub & PDF Apple & PC desktop. Mobile devices (Apple & Android) Amazon Kindle eReader
Mobi Amazon Kindle eReader Anything else

Institutional Access


Description

Introduction and Overview. Cortical Systems Involved in Appetite and Food Consumption. The Nucleus Accumbens Shell as a Model of Integrative Subcortical Forebrain Systems Regulating Food Intake. Hypothalamic Neuropeptides and the Regulation of Feeding. The Gut-Brain Axis in the Control of Eating. Integration of Peripheral Adiposity Signals and Psychological Controls of Appetite. Brain Reward Systems for Food Incentives and Hedonics in Normal Appetite and Eating Disorders. Pharmacology of Food, Taste and Learned Flavour Preferences. The Role of Palatability in Control of Human Appetite: Implications for Understanding and Treating Obesity. Learned Influences on Appetite, Food Choice and Intake. Gene Environment Interactions and the Origin of the Modern Obesity Epidemic. Pre-Clinical Developments in Anti-Obesity Drugs. Clinical Investigations of Anti-Obesity Drugs.

Key Features

  • Provides an integrative view of the many systems involved in appetite how they interact to effect food intake (i.e. the brain, endocrine, gut, liver etc.)
  • Considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts
  • Examines the development of novel anti-obesity drugs, drawing on experience of pharmacological development work, pre-clinical tests for anti-obesity efficacy, and clinical trials of candidate anti-obesity compounds

Readership

Neuroscientists, psychologists and pharmacologists undertaking research into mechanisms of action of anti-obesity drugs and the underlying psychological and physiological controls of appetite and body weight). This book is also written at a level that is approprite for ostgraduate classes (Masters), research students (PhD) and research fellows in these areas. In addition, this will appeal to established investigators in psychology, pharmacology, clinical medicine, and the pharmaceutical industry – specifically pharmacologists who are engaged in development work on novel anti-obesity compounds.

Table of Contents

Introduction and Overview. Cortical Systems Involved in Appetite and Food Consumption. The Nucleus Accumbens Shell as a Model of Integrative Subcortical Forebrain Systems Regulating Food Intake. Hypothalamic Neuropeptides and the Regulation of Feeding. The Gut-Brain Axis in the Control of Eating. Integration of Peripheral Adiposity Signals and Psychological Controls of Appetite. Brain Reward Systems for Food Incentives and Hedonics in Normal Appetite and Eating Disorders. Pharmacology of Food, Taste and Learned Flavour Preferences. The Role of Palatability in Control of Human Appetite: Implications for Understanding and Treating Obesity. Learned Influences on Appetite, Food Choice and Intake. Gene Environment Interactions and the Origin of the Modern Obesity Epidemic. Pre-Clinical Developments in Anti-Obesity Drugs. Clinical Investigations of Anti-Obesity Drugs.

Details

No. of pages:
384
Language:
English
Copyright:
© Academic Press 2007
Published:
Imprint:
Academic Press
eBook ISBN:
9780080466460
Hardcover ISBN:
9780123706331

About the Editor

Tim Kirkham

Affiliations and Expertise

University of Liverpool, UK

Steven Cooper

Affiliations and Expertise

University of Liverpool, UK