Apoptosis in Health and Disease - Part B

Apoptosis in Health and Disease - Part B

1st Edition - June 2, 2021

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  • Editor: Rossen Donev
  • eBook ISBN: 9780323853187
  • Hardcover ISBN: 9780323853170

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Apoptosis in Health and Disease - Part B, Volume 126 in the Advances in Protein Chemistry and Structural Biology focuses on apoptotic responses in numerous conditions - from bacterial and parasite infections, to pathological states such as oxidative stress, pulmonary hypertension, and different cancer types, etc. In addition, the book provides therapeutic strategies for targeting apoptosis. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target the cell death process. Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. Vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases.

Key Features

  • Integrates experimental and computational methods for studying apoptosis in health and different diseases
  • Includes strategies for identification of suitable therapeutic targets
  • Discusses the design of treatments targeting key points in the apoptotic cascade


Protein chemists, molecular cell biologists, immunologists, structural biologists, computational biochemists, medical doctors, pharmacologists and other researchers working in the field of transport proteins and drug design. Articles published here would also be of a considerable benefit to medical, biology and pharmacology students specializing in this field

Table of Contents

  • Contributors in the volume include:
    Santi Prasad Sinha Babu
    Soundarapandian KANNAN
    Soundarapandian KANNAN
    Dayanidhi Raman
    Gautam Sethi
    Mohammad Abid
    Pankaj Taneja
    Anupam Bishayee
    Harikumar KB
    Natella Enukashvily
    Sadhana R. Joshi
    Ali Akbar Moosavi-Movahedi

Product details

  • No. of pages: 356
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: June 2, 2021
  • Imprint: Academic Press
  • eBook ISBN: 9780323853187
  • Hardcover ISBN: 9780323853170

About the Editor

Rossen Donev

Rossen Donev
Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.

Affiliations and Expertise

Head of Research, MicroPharm Limited, UK

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