Anxiety, Volume 103

• Preface
• Chapter One: Stress, Anxiety, and Immunomodulation: A Pharmacological Analysis
  • Abstract
  • 1 Introduction
  • 2 Mechanism of Stress Response
  • 3 Stress, CNS, and Behavior
  • 4 Stress and Anxiety
  • 5 Stress and Various Anxiolytic Drugs
  • 6 Stress and Immunity
  • 7 Stress, Anxiety, and Immunomodulation
• Chapter Two: Estrogen Receptors Modulation of Anxiety-Like Behavior
  • Abstract
  • 1 Introduction
  • 2 Nuclear Estrogen Receptor Form and Function
  • 3 Estrogen Receptor Alpha
  • 4 Estrogen Receptor Beta
  • 5 G-Protein-Coupled Estrogen Receptor
  • 6 Cross Talk Between Estrogen Receptors
  • 7 Mechanisms for Estrogen Receptor Effects on Anxiety
  • 8 Conclusions
• Chapter Three: Neuroendocrine Underpinnings of Increased Risk for Posttraumatic Stress Disorder in Women
  • Abstract
  • 1 Introduction
  • 2 Case Example: PACAP Receptor Genetics
• Chapter Four: The Big Role of Small RNAs in Anxiety and Stress-Related Disorders
  • Abstract
  • 1 Introduction
  • 2 Epigenetics
  • 3 MicroRNAs
  • 4 Insights into miRNAs Through the Use of Animal Models
  • 5 Investigating miRNAs in Anxiety Disorders
  • 6 Conclusion
  • Acknowledgments
• Chapter Five: Natriuretic Peptides in Anxiety and Panic Disorder
  • Abstract
  • 1 Neuroendocrine Factors in Anxiety and Fear-Related Disorders
  • 2 Molecular Mechanisms Involved in Natriuretic Peptide Synthesis
  • 3 Expression of Natriuretic Peptides and Their Receptors in the Brain
  • 4 Physiological Actions of Natriuretic Peptides in the Brain
  • 5 Neuroprotective Effects of Natriuretic Peptides
  • 6 Evidence of Anxiolytic-Like Effects of ANP
• Chapter Six: Role of Nitric Oxide in Stress-Induced Anxiety: From Pathophysiology to Therapeutic Target
  • Abstract
  • 1 Introduction
  • 2 Summary
  • Acknowledgment
• Chapter Seven: Nitric Oxide and Anxiety
  • Abstract
  • 1 Introduction
  • 2 Nitric Oxide
  • 3 Conclusion
• Chapter Eight: The Endocannabinoid System and Anxiety
  • Abstract
  • 1 Introduction
  • 2 eCBs and Anxiety in Humans
  • 3 eCBs in Animal Models of Fear and Anxiety
  • 4 Brain Sites Modulating Cannabinoid Effects in Animal Models
  • 5 Additional Mechanisms Involved in the eCB Effects on Anxiety
  • 6 Closing Remarks and Future Directions
  • Acknowledgments
• Chapter Nine: The Melatonergic System in Anxiety Disorders and the Role of Melatonin in Conditional Fear
  • Abstract
  • 1 Introduction
  • 2 Anxiety and Melatonergic System
  • 3 PTSD and Pavlovian Fear Conditioning and Extinction
  • 4 Methods
  • 5 Results
  • 6 Discussion
  • Acknowledgments
• Chapter Ten: The Role of Elements in Anxiety
  • Abstract
  • 1 Introduction
  • 2 Animal Models of Anxiety
  • 3 Zinc
  • 4 Magnesium
  • 5 Copper
  • 6 Lithium
  • 7 Iron
  • 8 Manganese
  • 9 Conclusions
  • Acknowledgment
• Chapter Eleven: The Place of Stress and Emotions in the Irritable Bowel Syndrome
  • Abstract
  • 1 Introduction
  • 2 Pathophysiology of the IBS
  • 3 The Brain–Gut Axis
  • 4 The Output of the Central Autonomic Network and Stress Biological System
  • 5 Emotions and Stress in IBS
  • 6 Therapeutic Implications—Treatment Targeting Amygdala Activity Reduction and Vagal Tone Reinforcement in IBS: Mindfulness and Hypnosis
  • 7 Conclusion
• Index

Anxiety, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on the roles that hormones and other factors play in anxiety and stress.

Each volume focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances, such as transmitters, cytokines, growth factors, and others thoroughly reviewed.

• Provides cutting-edge reviews concerning the molecular and cellular biology of vitamins and hormones
• Contains expertise from world-renowned contributors
• Includes coverage of a vast array of subjects
• Presents in-depth, current information from the molecular to clinical level

Researchers, faculty, and graduate students interested in cutting-edge reviews concerning the molecular and cellular biology of vitamins, hormones, and related factors and co-factors. Libraries and laboratories at institutes with strong programs in cell biology, biochemistry, molecular biology, gene regulation, hormone control, and signal transduction are likely to be interested