Antimicrobial Dressings

Antimicrobial Dressings

The Wound Care Applications

1st Edition - April 1, 2023

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  • Editors: Raju Khan, Sorna Gowri
  • Paperback ISBN: 9780323950749

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Antimicrobial Dressings: The Wound Care Applications demonstrates the literature about the catalytic behavior of proteolytic enzymes immobilized together with nanoparticles. Numerous applications using proteolytic enzymes for debridement, silver as antibiotic and nanoparticles for enzyme immobilization were developed in the last years. However, the interdisciplinary information combining nanotechnology, biotechnology and medicine is still in its early stages. Antimicrobial Dressings: The Wound Care Applications adopts a holistic approach in a life cycle context to evaluate their final feasibility including industrial exploitability without disregard the potential risks of enzymes and nanomaterials to human health and the environment.

Key Features

  • describes the drawback of using unstable enzymes in wound debridement such as infections, irritations, low availability, rapid elimination from the body, and impossibility of creating a high local concentration of the preparation without increasing its systemic concentration
  • Provides information on higher efficient antimicrobial property and enzyme stability using nanoparticles as carriers for enzyme immobilization due to minimum diffusional limitation, maximum surface area per unit mass, and high enzyme loading
  • Discusses the physical characteristics of the nanoparticles through multilayer polyelectrolytes encasing, such as diffusion and particle mobility that will influence the catalytic activity, pH and thermal stability of attached enzymes
  • Describes the use of nanoparticles in wound debridement controlling the structure and properties of the assembled polyelectrolyte films at the molecular level and using nanoparticle with size higher than 30nm


Universities, institutes, and industrial Units, R&D institutes in microbiology, biotechnology, immunology students microbiologists / engineering colleges and universities/ Industrialists, Graduate students of research and development in the field of nanotechnology, medical and healthcare workers, commercial industries

Table of Contents

  • 1. Overview and Summary of Antimicrobial Activity in Wound Dressings and its Biomedical Applications

    2. Traditional and Modern Wound Dressings- Characteristics of Ideal Wound Dressings

    3. Nanoparticles as Potential Antimicrobial Agents for Enzyme Immobilization in Antimicrobial Wound Dressing

    4. Polyelectrolyte (PEM) Assembly With NP-Immobilized Enzymes

    5. Role of Debridement and its Biocompatibility in Antimicrobials Wound Dressing

    6. Different Immobilized-Enzyme Nanoparticles Multilayered Preparations

    7. Kinetic, Stability and Activity of the NP-Immobilized Enzymes

    8. The Antibacterial Hydrogel Dressings and their Applications in the Treatment of Wound

    9. Medicated Wound Dressings

    10. Clinical Effectiveness of Antimicrobial Dressing

    11. Future Research Directions of Antimicrobial Wound Dressing

Product details

  • No. of pages: 275
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: April 1, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780323950749

About the Editors

Raju Khan

Dr. Khan is currently working as Principal Scientist at Microfluidics & MEMS Centre, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal - 462026, MP, India. His current research on Bio-molecular separation, including sample preparation and detection, Microchip based separation under the concept of lab-on-a-chip and electrochemical biosensor integrated with microfluidics clinical applications. He has more than 15 years of R&D experience in CSIR & other academics R&D Institutes such as in Analytical Chemistry Group, CSIR-NEIST, Jorhat, Assam, CSIR-NPL, New Delhi and CSIR-AMPRI, Bhopal Govt. of India, respectively. He received his MSc degree in Inorganic Chemistry and Ph.D. in Physical Chemistry from Jamia Millia Islamia, Central University, New Delhi, India, in 2002 & 2005, respectively. After that, he worked as a Postdoctoral Fellow at the “Sensor Research laboratory” Department of Chemistry, University of the Western Cape, Cape Town, South Africa, in the year 2005-06 and also worked as a Fast-Track Young Scientist at CSIR-National Physical Laboratory, New Delhi Govt. of India. Dr. Khan is involved in synthesizing novel materials to fabricate electrochemical biosensors to detect target disease risk biomarker for health care monitoring. Dr. Khan is also engaged in other external project funding by the National & International collaborative project, Indo-Czech Republic & Indo-Russia. He is awarded the reputed BOYSCAST fellowship under the BOYSCAST fellowship scheme from DST and worked as a visiting scientist for one year at the University of Texas at San Antonio, UTSA, USA. Since then, he has published more than 80 articles in SCI journals which attracted more than 2700 citations, published nine book chapters in the reputed book of Elsevier and Taylor Francis, and he has also edited five books of Elsevier and Taylor Francis.

Affiliations and Expertise

Principal Scientist at Microfluidics and MEMS Centre, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal, MP, India

Sorna Gowri

V Sorna Gowri PhD is currently working as a Principal Technical officer, in CSIR-Advanced Materials and Processes Research Institute (AMPRI. Her recent research is on development of multifunctional nanocoatings on textiles. She has more than 21 years of R&D experience in CSIR-AMPRI, Bhopal Govt. of India. She worked as a Postdoctoral Fellow at Institute Curie, Paris France, and also worked as a Postdoctoral Fellow at University of Minho. Dr. S. Gowri was involved in synthesizing polymer nanocomposites for multifunctional surface coatings. She has published more than 21 SCI journals, Granted and Filed 2 patents. She is also team member of two technology transfers to industries

Affiliations and Expertise

Principal Technical officer, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal, India

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