Annual Reports in Organic Synthesis–1983 - 1st Edition - ISBN: 9780120408146, 9781483141169

Annual Reports in Organic Synthesis–1983

1st Edition

Annual Reports in Organic Synthesis

Editors: Martin J. O'Donnell Louis M. Weiss
eBook ISBN: 9781483141169
Imprint: Academic Press
Published Date: 20th August 1984
Page Count: 508
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Annual Reports in Organic Synthesis—1983 presents an annual review of synthetically useful information that would prove beneficial to nearly all organic chemists, both specialist and nonspecialist in synthesis. It should help relieve some of the information storage burden of the specialist and should aid the nonspecialist who is seeking help with a specific problem to become rapidly aware of recent synthetic advances. In producing this volume the editors abstracted 47 primary chemistry journals, selecting useful synthetic advances. All reactions and methods which are new, synthetically useful, and reasonably general are included. Each entry is comprised primarily of structures accompanied by very few comments. The purpose of this is to aid the reader in rapidly scanning the book.

Chapters I-III are organized by reaction type and constitute the major part of the book. Chapter IV deals with methods of synthesizing heterocyclic systems. Chapter V covers the use of new protecting groups. Chapter VI is divided into three main parts and covers those synthetically useful transformations that do not fit easily into the first three chapters. The first part deals only with functional group synthesis. The second part covers ring expansion and contraction, and the third part involves useful multistep sequences.

Table of Contents


Journals Abstracted

Glossary of Abbreviations

I. Carbon—Carbon Bond Forming Reactions

Carbon—Carbon Single Bonds (see also: I.E., I.F, I.G)

1. Alkylation of Aldehydes, Ketones, and Their Derivatives

2. Alkylations of Nitriles, Acids, and Acid Derivatives

3. Alkylation of ß-Dicarbonyl and ß-Cyanocarbonyl Systems and Other Active Methylene Compounds

4. Alkylation of N-, S-, and Se-Stabilized Carbanions

5. Alkylation of Organometallic Reagents (see also: I.F, I.G)

6. Other Alkylation Procedures and Reviews

7. Nucleophilic Addition of Electron-Deficient Carbon

8. Other Carbon—Carbon Single Bond Forming Reactions

B. Carbon—Carbon Double Bonds (see also: I.E.1, III.G, VI.A.16)

1. Wittig-Type Olefination Reactions

2. Eliminations

3. Other Carbon—Carbon Double Bond Forming Reactions

4. Allene Forming Reactions

C. Carbon—Carbon Triple Bonds (see also: VI.A.16)

D. Cyclopropanations

1. Carbene or Carbenoic Additions to a Multiple Bond (see also: VI.A.7)

2. Other Cyclopropanations

E. Thermal Reactions

1. Cycloadditions

2. Other Thermal Reactions

F. Aromatic Substitutions Forming a New Carbon—Carbon Bond

1. Friedel—Crafts-Type Reactions

2. Coupling Reactions

3. Other Aromatic Substitutions

G. Synthesis via Organometallics

1. Organoboranes

2. Carbonylation Reactions

3. Other Synthesis via Organometallics

4. Reviews

II. Oxidations

A. C—O Oxidations

1. Alcohol → Ketone, Aldehyde

2. Alcohol, Aldehyde → Acid, Acid Derivative

B. C—H Oxidations

1. C—H → C—O

2. C—H → C—Hal

3. Other C—H Oxidations

C. C—N Oxidations

D. Amine Oxidations

E. Sulfur Oxidations

F. Oxidative Additions to C—C Multiple Bonds

1. Epoxidations

2. Hydroxylation

3. Other

G. Phenol → Quinone Oxidation

H. Oxidative Cleavages

I. Photosensitized Oxygenations

J. Dehydrogenation

K. Other Oxidations and Reviews

III. Reductions

A. C = O Reductions (see also: III.F.1)

B. C-N Multiple Bond Reductions

1. Nitrile Reductions

2. Imine Reductions

C. Reduction of Sulfur Compounds

D. N—O Reductions

E. C—C Multiple Bond Reductions

1. C = C Reductions

2. C ≡ C Reductions

3. Reduction of Aromatic Rings

F. Hydrogenolysis of Hetero Bonds

1. C—O → C—H

2. C—Hal → C—H

3. C—S → C—H

4. C—N → C—H

G. Reductive Eliminations

H. Reductive Cleavages

I. Hydroboration (reduction only)

J. Other Reductions and Reviews

IV. Synthesis of Heterocycles

A. Aziridines

B. Furans, etc.

C. Indoles

D. Lactams

E. Lactones

F. Pyridines, Quinolines, etc.

G. Pyrroles, etc.

H. Other Heterocycles with One Heteroatom (see also: II.F.1, VI.A.9)

I. Heterocycles with Two or More Heteroatoms

1. Heterocycles with 2 Ns

2. Heterocycles with 1 N and 1 O

3. Heterocycles with 1 N and 1 S

4. Heterocycles with 1 S and 1 O

5. Heterocycles with 3 Ns

6. Other Heterocycles

J. General Reviews

V. Protecting Groups

A. Hydroxyl (see also: VI A.10, VI.A.11)

B. Amine (see also: VI.A.4)

C. Sulfhydryl (see also: VI.A.19)

D. Carboxyl (see also: VI.A.4, VI.A.10)

E. Ketone, Aldehyde (see also: VI.A.18)

F. Phosphate

G. Pi Bond

H. Miscellaneous Protecting Groups

VI. Useful Synthetic Preparations

A. Functional Group Preparations

1. Acids, Acid Halides, etc. (see also: II.A.2)

2. Alcohols, Phenols (see also: II.B.1, III.A., III.F.1)

3. Alkyl, Aryl Halides (see also: II.B.2)

4. Amides (see also: IV.D, VI.A.17)

5. Amines (see also: III.B.2, III.D)

6. Amino Acids and Derivatives (see also: III.E.1, VI.A.4, VI.A.10)

7. Carbenes (see also: I.D)

8. Enamines

9. Epoxides (see also: II.F.1, IV.H)

10. Esters (see also: IV.E, V.D)

11. Ethers (see also: V.A)

12. Ketones and Aldehydes (see also: I.A.2, II.A.1, III.F.1)

13. Nitriles

14. Nitro

15. Nucleotides, etc. (see also: IV.I.1a, b, V.F)

16. Olefins, Acetylenes (see also: I.B, I.C, II.J, III.G)

17. Peptides (see also: V.B, V.C, V.D, VI.A.4)

18. Vinyl Halides, Vinyl Ethers, Vinyl Esters

19. Sulfur Compounds (see also: II.E, III.C)

B. Ring Enlargement and Contraction

1. Enlargement

2. Contraction

C. Multistep Transformations

1. Masked Carbonyl Systems

2. Other Multistep Transformations

VII. Miscellaneous Reviews

Author Index


No. of pages:
© Academic Press 1984
Academic Press
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About the Editor

Martin J. O'Donnell

Louis M. Weiss

Louis M. Weiss

Louis M. Weiss M.D., M.P.H is Professor of Medicine (Division of Infectious Diseases) and Professor of Pathology (Division of Parasitology and Tropical Medicine) of the Albert Einstein College of Medicine, Bronx, New York. Dr. Weiss received his M.D. and M.P.H degrees from the Johns Hopkins University in 1982. He then completed a residency in Internal Medicine at the University of Chicago and a fellowship in Infectious Diseases at the Albert Einstein College of Medicine. Following this fellowship, he joined the faculty at Einstein where he is currently a Professor of Pathology and Medicine. His laboratory group has an active research program on parasitic diseases with a research focus on Toxoplasma gondii, the Microsporidia and Trypanosoma cruzi. Dr. Weiss is the author of over 200 publications and the editor of 3 books on parasitology. He is a fellow of the American College of Physicians, Infectious Disease Society of America and the American Academy of Microbiology. Dr. Weiss is the Co-Director of the Einstein Global Health Center.

Affiliations and Expertise

Professor of Medicine and Pathology, Albert Einstein College of Medicine of Yeshiva University, New York, U.S.A.

Ratings and Reviews