COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
An Invitation to Biomathematics - 1st Edition - ISBN: 9780120887712, 9780080550992

An Invitation to Biomathematics

1st Edition

Authors: Raina Robeva James Kirkwood Robin Davies Leon Farhy Boris Kovatchev Martin Straume Michael Johnson
Hardcover ISBN: 9780120887712
eBook ISBN: 9780080550992
Paperback ISBN: 9781493300051
Imprint: Academic Press
Published Date: 23rd August 2007
Page Count: 480
Sales tax will be calculated at check-out Price includes VAT/GST
Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.


Essential for all biology and biomathematics courses, this textbook provides students with a fresh perspective of quantitative techniques in biology in a field where virtually any advance in the life sciences requires a sophisticated mathematical approach. An Invitation to Biomathematics, expertly written by a team of experienced educators, offers students a solid understanding of solving biological problems with mathematical applications. This text succeeds in enabling students to truly experience advancements made in biology through mathematical models by containing computer-based hands-on laboratory projects with emphasis on model development, model validation, and model refinement.

The supplementary work, Laboratory Manual of Biomathematics is available separately ISBN 0123740223, or as a set ISBN: 0123740290)

Key Features

  • Provides a complete guide for development of quantification skills crucial for applying mathematical methods to biological problems
  • Includes well-known examples from across disciplines in the life sciences including modern biomedical research
  • Explains how to use data sets or dynamical processes to build mathematical models
  • Offers extensive illustrative materials
  • Written in clear and easy-to-follow language without assuming a background in math or biology
  • A laboratory manual is available for hands-on, computer-assisted projects based on material covered in the text


courses in mathematical biology, as well as in general mathematics and biology courses that cover the application of math and statistics to biological problems. The reader is not expected to have any extensive background in either math or biology.

Table of Contents

  1. Processes that Change with Time: Introduction to Dynamical Systems / 2. Complex Dynamics Emerging from Interacting Dynamical Systems / 3. Mathematics in Genetics / 4. Quantitative Genetics and Statistics / 5. Risk Analysis of Blood Glucose Data / 6. Predicting Septicemia in Neonates / 7. Cooperative Binding: How Your Blood Transports Oxygen / 8. Ligand Binding, Data Fitting, and Least-Squares Estimates of Model Parameters / 9. Endocrinology and Hormone Pulsatility / 10. Endocrine Network Modeling: Feedback Loops and Hormone Oscillations / 11. Detecting Rhythms in Confounded Data / 12. Using Microarrays to Study Gene Expression Patterns


No. of pages:
© Academic Press 2007
23rd August 2007
Academic Press
Hardcover ISBN:
eBook ISBN:
Paperback ISBN:

About the Authors

Raina Robeva

Raina Robeva

Raina Robeva was born in Sofia, Bulgaria. She holds a PhD in Mathematics from the University of Virginia and has broad research interests spanning theoretical mathematics, applied probability, and systems biology. Robeva is the founding Chief Editor of the journal Frontiers in Systems Biology and the lead author/editor of the books An Invitation to Biomathematics (2008), Mathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models (2013), and Algebraic and Discrete Mathematical Methods for Modern Biology (2015), all published by Academic Press. She is Professor of Mathematical Sciences and Director of the Center for Science and Technology in Society at Sweet Briar College.

Affiliations and Expertise

Professor of Mathematical Sciences, Sweet Briar College, VA, USA

James Kirkwood

Affiliations and Expertise

Sweet Briar College, Virginia, U.S.A.

Robin Davies

Affiliations and Expertise

Sweet Briar College, Virginia, U.S.A.

Leon Farhy

Boris Kovatchev

Dr. Boris Kovatchev is Professor at the University of Virginia School of Medicine and School of Engineering, and founding director of the Center for Diabetes Technology. He has a 30-year track record in mathematical modeling, biosimulation, and algorithm development. Currently, he is Principal Investigator of several projects dedicated to Diabetes Data Science and the development of artificial pancreas and decision support systems, including the large-scale NIH International Diabetes Closed-Loop Trial and the UVA Strategic Investment Fund project “Precision Individualized Medicine for Diabetes”. Dr. Kovatchev is author of over 200 peer-reviewed publications and holds 85 patents.

Affiliations and Expertise

Center for Diabetes Technology, Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, USA

Martin Straume

Affiliations and Expertise

University of Virginia, Center for Biomathematical Technology, U.S.A.

Michael Johnson

Affiliations and Expertise

University of Virginia Health Sciences Center, Charlottesville, USA


“I was impressed with the excellent job done by the authors…particularly, how the biology is explained first and then the math necessary to solve the problem is developed.” --Phil Ryan, Truman State University

“I would strongly recommend publication. This book will show young biologists how their existing mathematical skills can be put to powerful use in modern biology.” --Martin Steward, University of Manchester

Ratings and Reviews