An Introduction to Interdisciplinary Toxicology - 1st Edition - ISBN: 9780128136027

An Introduction to Interdisciplinary Toxicology

1st Edition

From Molecules to Man

Editors: Carey Pope Jing Liu
Paperback ISBN: 9780128136027
Imprint: Academic Press
Published Date: 1st February 2020
Page Count: 400
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Interdisciplinary Toxicology: From Molecules to Man provides a thorough exploration of the myriad field of toxicology. Toxicology has developed as an interdisciplinary field, and today’s world presents more complex toxicological problems than ever before, requiring expertise from various disciplines including environmental science, physiology, pharmacology, ecology and others. Importantly, technology and analytical/diagnostic/computational tools have expanded greatly, allowing for more sophisticated experimental approaches and requiring the evaluation of unprecedented amounts of data. Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology from “simple” molecular systems to complex human communities, with expertise from a spectrum of interacting disciplines.

Chapters are written by specialists within a subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so that these subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are included. Interdisciplinary Toxicology: From Molecules to Man allows students to learn concepts in both biomedical and environmental toxicology fields concurrently, better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology.

Key Features

    • Covers major topics and newer areas in toxicology including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity.
    • Includes a variety of perspectives to give a complete understanding of toxicology.
    • Written by specialists within subject areas, e.g., a chemical engineer, to ensure concepts are clearly explained.


    Graduate students and advanced undergraduate students in toxicology programs. Students and researchers in medicine, environmental sciences, neuroscience, food sciences, computing, and fundamental life sciences needing information about toxicology information in their discipline

    Table of Contents

    I. General Concepts
    1. Principles
    2. Sources of exposures: Point vs Nonpoint Source Contamination
    3. How chemicals distribute in the physical environment
    4. How chemicals distribute in cells and simple organisms
    5. How chemicals distribute in complex organisms

    II. Responses to chemical toxicants
    6. Cellular responses to toxicants
    7. Genotoxicity and epigenetics
    8. Carcinogenesis
    9. Disruption of cell signaling
    10. Altered development and reproduction
    11. Microbiome alterations and modulation of toxicity
    12. Nanotoxicology

    III. Organ System Effects
    13. Dermal system
    14. Gastrointestinal system
    15. Excretory system
    16. Respiratory System
    17. Cardiovascular system
    18. Musculoskeletal system
    19. Endocrine system
    20. The immune system
    21. Visual system
    22. Nervous system

    IV. Ecosystems and Ecotoxicology
    23. Organism vs population
    24. Bioconcentration
    25. Biomarkers

    V. Toxicology in the Home
    26. Opiates and other therapeutics
    27. Cleaning products
    28. Petroleum products

    VI. Toxicology in the Community
    29. Historical case studies
    30. Social factors in community contamination

    VII. Forensic Toxicology

    VIII. Regulatory Toxicology
    31. Toxicity testing
    32. Tox21
    33. Principles of Risk Assessment

    IX. Reference materials and websites
    34. Information Resources in Toxicology, 4th edition.
    35. National Toxicology Program
    36. National Center for Toxicological Research
    37. FDA
    38. EPA


    No. of pages:
    © Academic Press 2020
    Academic Press
    Paperback ISBN:

    About the Editor

    Carey Pope

    Dr. Pope is the author of over 95 peer-reviewed papers. He is the Director of the Interdisciplinary Toxicology Program at Oklahoma State University as well as a member of the Food Quality Protection Act (FQPA) Board, U.S. Environmental Protection Agency, Washington, D.C.. He sits on the Editorial Board of many journals including: • Toxicological Sciences • Journal of Toxicology and Environmental Health • International Journal of Toxicology • Toxicology • Toxicology and Applied Pharmacology • Journal of Environmental Science and Health Part C • NeuroToxicology • Archives of Toxicology

    Affiliations and Expertise

    Professor and Sitlington Endowed Chair in Toxicology, Department of Physiological Sciences, College of Veterinary Medicine; Director, Interdisciplinary Toxicology Program, Oklahoma State University-Stillwater

    Jing Liu

    Dr. Liu’s research interests include the neurochemical and neurobehavioral effects of xenobiotics. She is interested in exogenous and endogenous factors that modulate the neurotoxicological effects of pesticides and other neurotoxicants.

    Affiliations and Expertise

    Senior Research Scientist, Charles River Laboratories, Reno, NV; Adjunct Associate Professor, Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University-Stillwater

    Ratings and Reviews