Amyloid, Prions, and Other Protein Aggregates, Part C - 1st Edition - ISBN: 9780121828189, 9780080468976

Amyloid, Prions, and Other Protein Aggregates, Part C, Volume 413

1st Edition

Serial Volume Editors: Ronald Wetzel Indu Kheterpal
Hardcover ISBN: 9780121828189
eBook ISBN: 9780080468976
Imprint: Academic Press
Published Date: 6th October 2006
Page Count: 416
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Table of Contents

Characterization of protein deposition in vitro.

Chapter 1: Purification of Polyglutamine Proteins Chapter 2: Preparation of amyloid beta-protein for structural and functional studies. Chapter 3: Kinetics and thermodynamics of amyloid assembly using an HPLC-based sedimentation assay. Chapter 4: Protein aggregation starting from the native, globular stete. Chapter 5: Direct observation of amyloid growth monitored by total internal reflection fluorescence microscopy. Chapter 6: Characterization of Amyloid Structures at the Molecular Level by Solid State Nuclear Magnetic Resonance Spectroscopy. Chapter 7: Spin Labeling Analysis of Amyloids and other Protein Aggregates. Chapter 8: Hydrogen-Deuterium Exchange Mass Spectrometry of Protein Aggregates.


Description

Characterization of protein deposition in vitro.

Chapter 1: Purification of Polyglutamine Proteins Chapter 2: Preparation of amyloid beta-protein for structural and functional studies. Chapter 3: Kinetics and thermodynamics of amyloid assembly using an HPLC-based sedimentation assay. Chapter 4: Protein aggregation starting from the native, globular stete. Chapter 5: Direct observation of amyloid growth monitored by total internal reflection fluorescence microscopy. Chapter 6: Characterization of Amyloid Structures at the Molecular Level by Solid State Nuclear Magnetic Resonance Spectroscopy. Chapter 7: Spin Labeling Analysis of Amyloids and other Protein Aggregates. Chapter 8: Hydrogen-Deuterium Exchange Mass Spectrometry of Protein Aggregates.

Key Features

  • Presents detailed protocols
  • Includes troubleshooting tips
  • Provides coverage on structural biology, computational methods, and biology

Readership

Biochemists, cell biologists, neuroscientists, and related fields engaged in protein research.


Details

No. of pages:
416
Language:
English
Copyright:
© Academic Press 2006
Published:
Imprint:
Academic Press
eBook ISBN:
9780080468976
Hardcover ISBN:
9780121828189

About the Serial Volume Editors

Ronald Wetzel Serial Volume Editor

Affiliations and Expertise

University of Tennessee Medical Center, Knoxville, U.S.A.

Indu Kheterpal Serial Volume Editor