Description

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

Key Features

@introbul:Key Features @bul:* This volume includes reviews on some of the hottest topics in pharmacology, including: * Multidrug resistance and the MDR1 gene in gene therapy * Regulation of calcium channels in epithelial cells * Gene therapy and vascular disease * Potential therapeutic applications for Heparin * Calcium channel blockers * Antithrombotic agents * Regulation of potassium channels in epithelial cells

Readership

Pharmacologists, immunologists, and biochemists.

Table of Contents

J. M. Aran, I. Pastan, and M. Gottesman, Therapeutic Strategies Involving the Multidrug Resistance Phenotype: The MDRI Gene as a Target, Chemoprotectant and Selectable Marker in Gene Therapy. R. G. O'Neil and M. I. N. Zhang, The Diversity of Calcium Channels and Their Regulation in Epithelial Cells. M. Kibbe, T. Billiar, and E. Tzeng, Gene Therapy and Vascular Disease. D. J. Tyrell, A. P. Horne, K. R. Holme, J. M. H. Preuss, and C. P. Page, Heparin in Inflammation: Potential Therapeutic Applications Beyond Anticoagulation. A. P. Morris, The Regulation of Epithelial Cell cAMP- and Calcium-dependent Chloride Channels. W. T. Clusin and M. E. Anderson, Calcium Channel Blockers: Current Controversies and Basic Mechanisms of Action. K. K. Wu, Antithrombotic Agents. S. Schultz, Regulation of Potassium Channels in Sodium Absorbing Epithelial Cells.

Details

No. of pages:
344
Language:
English
Copyright:
© 1999
Published:
Imprint:
Academic Press
eBook ISBN:
9780080581385
Print ISBN:
9780120329472
Print ISBN:
9780123917607

About the serial-volume-editors

J. August

Affiliations and Expertise

John Hopkins University; Department of Pharmacology, Baltimore, Maryland, U.S.A.

M. Anders

Affiliations and Expertise

University of Rochester; Department of Pharmacology, New York, U.S.A.

Ferid Murad

Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children.

Affiliations and Expertise

University of Texas Medical School, Houston, U.S.A.

Joseph Coyle

Affiliations and Expertise

McLean Hospital, Harvard Medical School, Belmont, Massachusetts, U.S.A.

Reviews

@from:Praise for the Series @qu:"Recommended not only to pharmacologists but also to all those in related disciplines." @source:--NATURE @qu:"The works do represent an extensive compilation of data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated." @source:--H.E. Kaufmann in CHEMOTHERAPY @qu:"Superb reading material." @source:--JOURNAL OF PHARMACEUTICAL SCIENCES