Advances in Pharmacology, Volume 46

1st Edition

Print ISBN: 9780123917607
eBook ISBN: 9780080581385
Imprint: Academic Press
Published Date: 5th May 1999
Page Count: 344
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Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

Key Features

@introbul:Key Features @bul:* This volume includes reviews on some of the hottest topics in pharmacology, including:

  • Multidrug resistance and the MDR1 gene in gene therapy
  • Regulation of calcium channels in epithelial cells
  • Gene therapy and vascular disease
  • Potential therapeutic applications for Heparin
  • Calcium channel blockers
  • Antithrombotic agents
  • Regulation of potassium channels in epithelial cells


Pharmacologists, immunologists, and biochemists.

Table of Contents

J. M. Aran, I. Pastan, and M. Gottesman, Therapeutic Strategies Involving the Multidrug Resistance Phenotype: The MDRI Gene as a Target, Chemoprotectant and Selectable Marker in Gene Therapy.

R. G. O'Neil and M. I. N. Zhang, The Diversity of Calcium Channels and Their Regulation in Epithelial Cells.

M. Kibbe, T. Billiar, and E. Tzeng, Gene Therapy and Vascular Disease.

D. J. Tyrell, A. P. Horne, K. R. Holme, J. M. H. Preuss, and C. P. Page, Heparin in Inflammation: Potential Therapeutic Applications Beyond Anticoagulation.

A. P. Morris, The Regulation of Epithelial Cell cAMP- and Calcium-dependent Chloride Channels.

W. T. Clusin and M. E. Anderson, Calcium Channel Blockers: Current Controversies and Basic Mechanisms of Action.

K. K. Wu, Antithrombotic Agents.

S. Schultz, Regulation of Potassium Channels in Sodium Absorbing Epithelial Cells.


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© Academic Press 1999
Academic Press
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@from:Praise for the Series @qu:"Recommended not only to pharmacologists but also to all those in related disciplines." @source:--NATURE @qu:"The works do represent an extensive compilation of data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated." @source:--H.E. Kaufmann in CHEMOTHERAPY @qu:"Superb reading material." @source:--JOURNAL OF PHARMACEUTICAL SCIENCES