Advances in Lipid Research

Advances in Lipid Research

1st Edition - December 28, 1989

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  • Editors: Rodolfo Paoletti, David Kritchevsky
  • eBook ISBN: 9781483215440

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Advances in Lipid Research, Volume 23 provides information pertinent to mammalian as well as plant metabolism. This book presents important data on apoproteins, which may offer a foothold for further probes of the genetics underlying increased susceptibility to ischemic heart disease. Organized into seven chapters, this volume begins with an overview of the molecular biology of human apolipoproteins B and E. This text then explains the lipid metabolism of dermatophytes and describes their lipid composition and how it may be modulated. Other chapters consider the function, distribution, and biosynthesis of the sterols of fungi and examine the influences of fungal sterols on membrane fluidity. This book discusses as well the biosynthesis and degradation of platelet-activating factor (PAF) as well as its physiological function. The final chapter deals with one specific area of PAF activity, namely, renal processes. This book is a valuable resource for biologist, biochemists, chemists, and clinicians.

Table of Contents

  • Preface

    Molecular Biology of Human Apolipoproteins B and E and Associated Diseases of Lipoprotein Metabolism

    I. General Introduction

    II. Apolipoprotein B

    III. Apolipoprotein E

    IV. Conclusions


    Lipids of Dermatophytes

    I. Introduction

    II. Lipid Composition

    III. Modulation of Lipid Composition

    IV. Biosynthesis and Turnover of Lipids

    V. Biosynthetic Enzymes of Phospholipids

    VI. Catabolic Enzymes

    VII. Role of Membrane Lipids

    VIII. Lipids and Antifungal Drugs

    IX. Allergenicity of Fungal Lipids

    X. Conclusion


    Structure and Function of Sterols in Fungi

    I. Introduction

    II. Structure and General Occurrence

    III. Distribution among Fungal Taxa

    IV. Production, Biosynthesis, and Inhibition

    V. Sterol Functions

    VI. Overview


    Dietary Polyunsaturated Fatty Acids and Eicosanoid Formation in Humans

    I. Introduction

    II. Dietary Polyunsaturated Fatty Acids

    III. Eicosanoid Formation in Humans

    IV. Manipulation of the Eicosanoid System

    V. Dietary n-6 Polyunsaturated Fatty Acids and Eicosanoid Formation

    VI. Dietary n-3 Polyunsaturated Fatty Acids and Eicosanoid Formation

    VII. Unresolved Questions and Issues


    Analysis of Eicosanoid Formation in Humans by Mass Spectrometry

    I. Introduction

    II. Problems of Analysis

    III. Strategies for Analysis

    IV. Locations for Analysis in Humans

    V. Extraction and Separation Methods

    VI. Analysis by Mass Spectrometry


    The Synthesis, Catabolism, and Pathophysiological Role of Platelet-Activating Factor

    I. Introduction

    II. Synthesis of PAF

    III. PAF Catabolism

    IV. Mechanism of PAF-Induced Cell Activation

    V. PAF Antagonists

    VI. Pathophysiological Role of PAF

    VII. Concluding Remarks


    Involvement of Platelet-Activating Factor in Renal Processes

    I. Introduction

    II. Generation of PAF

    III. Relationship Between PAF and Other Inflammatory Mediators

    IV. Physiological Effects of PAF

    V. Role of PAF in Renal Diseases

    VI. Conclusion



    Contents of Previous Volumes

Product details

  • No. of pages: 316
  • Language: English
  • Copyright: © Academic Press 1989
  • Published: December 28, 1989
  • Imprint: Academic Press
  • eBook ISBN: 9781483215440

About the Editors

Rodolfo Paoletti

David Kritchevsky

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