This volume highlights the latest reviews of mechanisms and actions of the immune system and the host response to infection and inflammation.

Key Features

@introbul:Key Features @bul:* Covers cytokine functioning as influenced by the Janus protein tyrosine kinase family * Explores immunodeficiencies, including: @subbul:* Immunoglobulin deficiencies and B cells development * Glycosyl Phosphatidylinositol (GPI)-anchor and Paroxysmal Nocturnal Hemoglobinuria (PNH) * Investigates the links molecular pathology established between deficiencies in GPI-anchor synthesis and PNH * Includes the use of Multiple Antigen Peptides (MAPs) to induce protective immune response * Offers a timely update on Eosinophils' role in disease * Covers histology of Germinal center reaction of a spleen twelve days after primary immunization * Includes new research on cytotoxic T-lymphocytes * Presents the multiple roles of Nitric oxide (NO) in the inflammatory response


Researchers and graduate students in immunology, cell and molecular biology, and toxicology in academia, medicine, and industry.

Table of Contents

J.N. Ihle, The Janus Protein Tyrosine Kinase Family and Its Role in Cytokine Signaling. R. Fuleihan, N. Ramesh, and R.S. Geha, X-Linked Agammaglobulinemia and Immunoglobulin Deficiency with Normal or ElevatedIgM: Immunodeficiencies of B Cell Development and Differentiation. T. Kinoshita, N. Inoue, and J. Takeda, Defective Glycosyl Phosphatidylinositol Anchor Synthesis and Paroxysmal Nocturnal Hemoglobinuria. E.H. Nardin, G.A. Oliveira, J.M. Calvo-Calle, and R.S. Nussenzweig, The Use of Multiple Antigen Peptides in the Analysis and Induction of Protective Immune Responses against Infectious Diseases. A.J. Wardlaw, R. Moqbel, and A.B. Kay, Eosinophils: Biology and Role in Disease. G. Kelsoe, In Situ Studies of the Germinal Center Reaction. H. Takayama, H. Kojima, and N. Shinohara, Cytotoxic T Lymphocytes: The Newly Identified Fas (CD95)-Mediated Killing Mechanism and a Novel Aspect of Their Biological Functions. C.R. Lyons, The Role of Nitric Oxide in Inflammation. References. Subject Index. Contents of Recent Volumes.


No. of pages:
© 1995
Academic Press
eBook ISBN:
Print ISBN:

About the serial-volume-editor

Frank Dixon

Affiliations and Expertise

The Scripps Research Institute, La Jolla, California, U.S.A.


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