Advances in Immunology - 1st Edition - ISBN: 9780128022443, 9780128024324

Advances in Immunology, Volume 126

1st Edition

Editors: Frederick Alt
eBook ISBN: 9780128024324
Hardcover ISBN: 9780128022443
Imprint: Academic Press
Published Date: 26th February 2015
Page Count: 244
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Table of Contents

    <li>Chapter One: NOD.H-2h4 Mice: An Important and Underutilized Animal Model of Autoimmune Thyroiditis and Sjogren's Syndrome<ul><li>Abstract</li><li>1 Introduction</li><li>2 Spontaneous Autoimmune Thyroiditis</li><li>3 TEC Hyperplasia/Proliferation</li><li>4 NOD.H-2h4 Mice Can Be Used as a Model of Experimentally Induced Autoimmune Thyroiditis</li><li>5 SS in NOD.H-2h4 Mice and NOD.H-2h4 Mutants</li><li>6 Concluding Remarks</li><li>Acknowledgments</li></ul></li> <li>Chapter 2: Approaches for Analyzing the Roles of Mast Cells and Their Proteases <i>In Vivo</i><ul><li>Abstract</li><li>1 Mast Cell Biology</li><li>2 Nongenetic Approaches for Analyzing the Functions of Mast Cells and Mast Cell-Associated Proteases <i>In Vivo</i></li><li>3 Genetic Approaches for Analyzing the Functions of Mast Cells <i>In Vivo</i></li><li>4 Genetic Approaches for Analyzing the Functions of Mast Cell-Associated Proteases <i>In Vivo</i></li><li>5 Using Mast Cell-Deficient or Mast Cell-Associated Protease-Deficient Mice to Analyze Functions of Mast Cells or Their Proteases <i>In Vivo</i></li><li>6 General Recommendations Regarding the Use of Mast Cell-Deficient or Mast Cell-Associated Protease-Deficient Mice to Analyze Biological Responses <i>In Vivo</i></li><li>7 Perspective</li><li>Acknowledgments</li></ul></li> <li>Chapter 3: Epithelial Cell Contributions to Intestinal Immunity<ul><li>Abstract</li><li>1 Introduction</li><li>2 Cellular Makeup of the Intestinal Epithelial Barrier</li><li>3 Epithelial Cell Sensing of Intestinal Microbes</li><li>4 Mucus Production by the Intestinal Epithelium</li><li>5 Epithelial Antimicrobial Proteins</li><li>6 Intestinal Epithelial Cell Autophagy</li><li>7 Epithelial Regulation of Adaptive Immunity</li><li>8 Bacterial Stimulation of Epithelial Cell Repair</li><li>9 Epithelial Dysfunction in Inflammatory Disease</li><li>10 Future Perspectives</li><li>Acknowledgments</li></ul></li> <li>Chapter 4: Innate Memory T cell


Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field


Immunologists and infectious disease specialists, cell biologists and hematologists.


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© Academic Press 2015
Academic Press
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"The series which all immunologists need." --The Pharmaceutical Journal

"Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions." --Science

"Deserves a permanent place in biomedical libraries as an aid in research and in teaching." --Journal of Immunological Methods

Ratings and Reviews

About the Editors

Frederick Alt Editor

Affiliations and Expertise

Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA