Advances in Carbohydrate Chemistry and Biochemistry

Advances in Carbohydrate Chemistry and Biochemistry

1st Edition - December 4, 2021

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  • Editor: David Baker
  • eBook ISBN: 9780323851121
  • Hardcover ISBN: 9780128246283

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Advances in Carbohydrate Chemistry and Biochemistry, Volume 80 highlights new advances in the field, with this new volume presenting interesting chapters on a range of topics, including Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2π Partners for the Synthesis of Functionalized Sugars, Enantiomerically Pure Carbocycles and Heterocycles and a Biographical Memoire for Leslie Hough.

Key Features

  • Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research
  • Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates
  • Informs and updates on all the latest developments in the field


Researchers in biochemistry, organic chemistry, carbohydrate chemistry/ biochemistry, medicinal chemistry, and instrumentation methodology

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Contributors
  • Preface
  • References
  • Chapter One: Combining computational and experimental studies for a better understanding of cellulose and its analogs
  • Abstract
  • 1: Introduction
  • 2: From primitive models to atomistic details
  • 3: The limit of experimental determination
  • 4: Modeling crystals and prediction of experimental response
  • 5: Understanding the underlying interactions and thermodynamics
  • 6: Conclusions
  • References
  • Chapter Two: Combining Computational Chemistry and Crystallography for a Better Understanding of the Structure of Cellulose
  • Abstract
  • I: Introduction
  • II: Information from Crystals of Related Small Molecules
  • III: Energy Calculations
  • IV: Detection of New Stabilizing Interactions in Cellulose with Atoms-in-Molecules Theory
  • V: Modeling Crystals of Cellulose
  • VI: Conclusions
  • Appendix: Molecular Structure Drawings for Saccharide Analogues Having β-(1 → 4) Linkages
  • References
  • Note Added in Proof
  • Chapter Three: Recent advances on glycosyltransferases involved in the biosynthesis of the proteoglycan linkage region
  • Abstract
  • 1: Xylosyltransferase-I/II
  • 2: β-1,4-Galactosyltransferase 7
  • 3: Future outlook
  • Acknowledgments
  • References
  • Chapter Four: Strategies in Synthesis of Heparin/Heparan Sulfate Oligosaccharides: 2000–Present
  • Abstract
  • I: Introduction
  • II: Linear Synthesis
  • III: Active–Latent Glycosylation Strategy
  • IV: Selective Activation
  • V: Reactivity-Based Chemoselective Glycosylation
  • VI: Reactivity-Independent, Pre-Activation-Based, Chemoselective Glycosylation
  • VII: Chemoenzymatic Synthesis
  • VIII: Future Outlook
  • Acknowledgments
  • References
  • Author index
  • Subject Index

Product details

  • No. of pages: 192
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: December 4, 2021
  • Imprint: Academic Press
  • eBook ISBN: 9780323851121
  • Hardcover ISBN: 9780128246283

About the Editor

David Baker

Prof. David C. Baker has a broad research and teaching experience in the organic and medicinal chemistry of the carbohydrates, including nucleosides and cell-surface carbohydrates that are documented in over 200 publications, presentations, and patents. He was elected a Fellow of the American Chemical Society where he has been active principally in the Division of Carbohydrate Chemistry.

Affiliations and Expertise

Professor of Chemistry, University of Tennessee in Knoxville, TN, USA

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