Advances in Carbohydrate Chemistry and Biochemistry, Volume 73

Chapter One: Stevia Glycosides: Chemical and Enzymatic Modifications of Their Carbohydrate Moieties to Improve the Sweet-Tasting Quality

• Abstract
• 1 Introduction
• 2 Steviol Glycoside Structures from S. rebaudiana
• 3 Steviol Variants of Glycoside Structures from S. rebaudiana
• 4 Stability of Steviol Glycosides
• 5 Structure–Sweetness Relationship
• 6 Chemical Modifications of Steviol Glycosides
• 7 Enzymatic Modifications of Steviol Glycosides
• 8 Patents Regarding Enzymatic Modifications of Steviol Glycosides
• 9 Concluding Remarks
• Addendum
• Acknowledgments

Chapter Two: Endoglycosidases for the Synthesis of Polysaccharides and Glycoconjugates

• Abstract
• 1 Introduction
• 2 Endoglycosidases in the Synthesis of Natural and Artificial Polysaccharides
• 3 Endoglycosidases in the Synthesis of N-Glycopeptides and N-Glycoproteins
• 4 Endoglycosidases for the Synthesis of Neoglycolipids and Glycosphingolipids
• 5 Concluding Remarks
• Acknowledgment

Chapter Three: Recent Advances Toward Robust N-Protecting Groups for Glucosamine as Required for Glycosylation Strategies

• Abstract
• 1 Introduction
• 2 The Glycosylation Reaction
• 3 Acyclic N-Protecting Groups
• 4 Cyclic N-Protecting Groups
• 5 Latent Amino-Protecting Groups
• 6 Conclusions
• Acknowledgments

Chapter Four: Carbohydrate-Processing Enzymes of the Lysosome: Diseases Caused by Misfolded Mutants and Sugar Mimetics as Correcting Pharmacological Chaperones

• Abstract
• 1 Introduction
• 2 Carbohydrate-Processing Enzymes of the Glycosphingolipid Degradation Pathway
• 3 Lysosomal Glycogen Degradation and Glycogen Storage Disease
• 4 Enzymes of the Glycoprotein Degradation Pathway and Glycoproteinoses
• 5 Enzymes Involved in Mucopolysaccharide Degradation and Mucopolysaccharidoses
• 6 Conclusions and Outlook

Advances in Carbohydrate Chemistry and Biochemistry has provided, since its inception in 1945, critical and informative articles written by research specialists that integrate the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology to the study of carbohydrates. Its articles present a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

• Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry, and research
• Integrates the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates
• Informs and updates on all the latest developments in the field

Researchers in biochemistry, organic chemistry, medicinal chemistry and instrumentation methodology