Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics


Researchers and students in the basic and clinical sciences of cancer biology and oncology, plus related areas in genetics, immunology, pharmacology, cell biology, and molecular biology.

Table of Contents

Chapter 1

Hedgehog Signaling and Pancreatic Tumor Development

Matthias Lauth and Rune Toftgård

Chapter 2

The Microenvironment and Molecular Biology of the Multiple Myeloma Tumor

Miguel Lemaire, Sarah Deleu, Elke De Bruyne, Els Van Valckenborgh, Eline Menu, and Karin Vanderkerken


Chapter 3

Chromatin Insulators: A Role in Nuclear Organization and Gene Expression

Jingping Yang and Victor G. Corces


Chapter 4

Proteolytic Control of the Oncoprotein Transcription Factor Myc

Lance R. Thomas and William P. Tansey


Chapter 5

TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade

Thierry Soussi



No. of pages:
© 2011
Academic Press
eBook ISBN:
Print ISBN:

About the editors

George Vande Woude

Affiliations and Expertise

Director, Van Andel Research Institute, Grand Rapids, MI, USA NCI-Frederick Cancer Research Facility Frederick, Maryland ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland

George Klein

Affiliations and Expertise

Karolinska Insitutet, Stockholm, Sweden


Praise for the Serial
"This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences." --American Scientist
"Excellent, highly informative, in-depth reviews…expertly written, up-to-date, and well-referenced." --Journal of Medicinal Chemistry
"This is a series that has a long tradition of excellence in the field of cancer biology." --Doody’s Publishing Reviews