Advances in Cancer Research - 1st Edition - ISBN: 9780120066674, 9780080562490

Advances in Cancer Research, Volume 67

1st Edition

Serial Volume Editors: George Vande Woude George Klein
eBook ISBN: 9780080562490
Imprint: Academic Press
Published Date: 20th October 1995
Page Count: 328
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Table of Contents

Foundations in Cancer Research Article:

A.G. Knudson, Jr., Mutation and Cancer: A Personal Odyssey.

Regular Articles:

A.T. Look, Oncogenic Role of "Master" Transcription Factors in Human Leukemias and Sarcomas: A Developmental Model.

B. Dutrillaux, Pathways of Chromosome Alteration in Human Epithelial Cancers.

T.A. Dragani, G. Manenti, and M.A. Pierotti, Genetics of Murine Lung Tumors.

G. Gaidano and R. Dalla-Favera, Molecular Pathogenesis of AIDS-Related Lymphomas.

F. Garrido, T. Cabrera, M.A. Lopez-Nevot, and F. Ruiz-Cabello, HLA Class I Antigens in Human Tumors.

J.W. Gratama and I. Ernberg, Molecular Epidemiology of Epstein-Barr Virus Infection.

E.M. Rosen and I.D. Goldberg, Scatter Factor and Angiogenesis.

M. Shibuya, A Review on the Role of VEGF-Flt Receptor System in Normal and Tumor Angiogenesis. References. Subject Index.


Description

Advances in Cancer Research is a biannual publication that includes timely reviews on the most cutting-edge issues in cancer research. Topics covered in Volume 67 include a developmental model of progenitor cell oncogenesis based on a description of transcriptional control; pathways of chromosome alteration in human epithelial cancers, using colorectal, breast, lung, and endometrial cancers as examples; the genetics of murine lung tumors; the molecular pathogenesis of AIDS-related lymphomas; HLA class I antigens in human tumors, focusing on abnormal MHC expression detected in human tumors and the biological role these alterations may have in tumor development; a summary of the information obtained by the molecular characterization of EBV diversity and discussion of its relevance for viral epidemiology, transmission, and pathogenesis. There are two reviews discussing angiogenesis: the first focuses on the role of scatter factor and the second, the VEGF-FH receptor system. The "Foundations in Cancer Research" article by Alfred G. Knudson is a personal account of his career studying mutation and cancer.

Key Features

  • A "Foundations in Cancer Research" article by Alfred G. Knudson, a personal account of his career studying mutation and cancer
  • A developmental model of progenitor cell oncogenesis based on a disruption of transcriptional control
  • Pathways of chromosome alteration in human epithelial cancers, using colorectal, breast, lung, and endometrial cancers as examples
  • A review of the genetics of murine lung tumors
  • Molecular pathogenesis of AIDS-related lymphomas
  • HLA class I antigens in human tumors, focusing on abnormal MHC expression detected in human tumors and the biological role these alterations may have in tumor development
  • A summary of the information obtained by the molecular characterization of EBV diversity and discussion of its relevance for viral epidemiology, transmission, and pathogenesis
  • The role of scatter factor in angiogenesis
  • The role of the VEGF-FH receptor system in normal and tumor angiogenesis

Details

No. of pages:
328
Language:
English
Copyright:
© Academic Press 1995
Published:
Imprint:
Academic Press
eBook ISBN:
9780080562490

Reviews

Praise for the Series
"This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences." --AMERICAN SCIENTIST

"Excellent, highly informative, in-depth reviews... expertly written, up-to-date, and well-referenced." --JOURNAL OF MEDICINAL CHEMISTRY

"Oncologists as well as other researchers and clinicians employing interferon will find this survey of interest." --BIOLOGICAL ABSTRACTS


About the Serial Volume Editors

George Vande Woude Serial Volume Editor

Affiliations and Expertise

Director, Van Andel Research Institute, Grand Rapids, MI, USA NCI-Frederick Cancer Research Facility Frederick, Maryland ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland

George Klein Serial Volume Editor

Affiliations and Expertise

Karolinska Insitutet, Stockholm, Sweden