Advances in Cancer Research

Advances in Cancer Research

1st Edition - October 20, 1995

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  • Editors: George Vande Woude, George Klein
  • eBook ISBN: 9780080562490

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Description

Advances in Cancer Research is a biannual publication that includes timely reviews on the most cutting-edge issues in cancer research. Topics covered in Volume 67 include a developmental model of progenitor cell oncogenesis based on a description of transcriptional control; pathways of chromosome alteration in human epithelial cancers, using colorectal, breast, lung, and endometrial cancers as examples; the genetics of murine lung tumors; the molecular pathogenesis of AIDS-related lymphomas; HLA class I antigens in human tumors, focusing on abnormal MHC expression detected in human tumors and the biological role these alterations may have in tumor development; a summary of the information obtained by the molecular characterization of EBV diversity and discussion of its relevance for viral epidemiology, transmission, and pathogenesis. There are two reviews discussing angiogenesis: the first focuses on the role of scatter factor and the second, the VEGF-FH receptor system. The "Foundations in Cancer Research" article by Alfred G. Knudson is a personal account of his career studying mutation and cancer.

Key Features

  • A "Foundations in Cancer Research" article by Alfred G. Knudson, a personal account of his career studying mutation and cancer
  • A developmental model of progenitor cell oncogenesis based on a disruption of transcriptional control
  • Pathways of chromosome alteration in human epithelial cancers, using colorectal, breast, lung, and endometrial cancers as examples
  • A review of the genetics of murine lung tumors
  • Molecular pathogenesis of AIDS-related lymphomas
  • HLA class I antigens in human tumors, focusing on abnormal MHC expression detected in human tumors and the biological role these alterations may have in tumor development
  • A summary of the information obtained by the molecular characterization of EBV diversity and discussion of its relevance for viral epidemiology, transmission, and pathogenesis
  • The role of scatter factor in angiogenesis
  • The role of the VEGF-FH receptor system in normal and tumor angiogenesis

Table of Contents

  • Foundations in Cancer Research Article:
    A.G. Knudson, Jr., Mutation and Cancer: A Personal Odyssey.
    Regular Articles:
    A.T. Look, Oncogenic Role of "Master" Transcription Factors in Human Leukemias and Sarcomas: A Developmental Model.
    B. Dutrillaux, Pathways of Chromosome Alteration in Human Epithelial Cancers.
    T.A. Dragani, G. Manenti, and M.A. Pierotti, Genetics of Murine Lung Tumors.
    G. Gaidano and R. Dalla-Favera, Molecular Pathogenesis of AIDS-Related Lymphomas.
    F. Garrido, T. Cabrera, M.A. Lopez-Nevot, and F. Ruiz-Cabello, HLA Class I Antigens in Human Tumors.
    J.W. Gratama and I. Ernberg, Molecular Epidemiology of Epstein-Barr Virus Infection.
    E.M. Rosen and I.D. Goldberg, Scatter Factor and Angiogenesis.
    M. Shibuya, A Review on the Role of VEGF-Flt Receptor System in Normal and Tumor Angiogenesis.
    References.
    Subject Index.

Product details

  • No. of pages: 328
  • Language: English
  • Copyright: © Academic Press 1995
  • Published: October 20, 1995
  • Imprint: Academic Press
  • eBook ISBN: 9780080562490

About the Serial Volume Editors

George Vande Woude

Affiliations and Expertise

Director, Van Andel Research Institute, Grand Rapids, MI, USA NCI-Frederick Cancer Research Facility Frederick, Maryland ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland

George Klein

Affiliations and Expertise

Karolinska Insitutet, Stockholm, Sweden

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