Advances in Biomembranes and Lipid Self-Assembly, Volume 23

Chapter One: The Importance of Planarity for Lipid Bilayers as Biomembranes

• Abstract
• 1 Introduction
• 2 How CPP Translocates into the Cytosol
• 3 Pore Formation
• 4 How Does Curvature Modulation by Changing Vesicle Size Effect the CPP Translocation?
• 5 Conclusion
• Acknowledgments

Chapter Two: Interaction of Cells and Platelets with Biomaterial Surfaces Treated with Gaseous Plasma

• Abstract
• 1 Introduction
• 2 Experimental
• 3 Results
• 4 Discussion
• 5 Conclusions

Chapter Three: Competition Between Electrostatic and Thermodynamic Casimir Potentials in Near-Critical Mixtures with Ions

• Abstract
• 1 Introduction
• 2 Experiments
• 3 From Microscopic to Mesoscopic Description
• 4 Critical Mixture with Inorganic Ions
• 5 Critical Mixture with Antagonistic Salt
• 6 Summary
• Acknowledgments

Chapter Four: Effect of Dendrimers and Dendriplexes on Model Lipid Membranes

• Abstract
• 1 Introduction
• 2 Carbosilane Dendrimers
• 3 Phosphorus Dendrimers
• 4 PAMAM Dendrimers
• 5 Conclusions
• Acknowledgments

Chapter Five: The Membrane Bending Modulus in Experiments and Simulations: A Puzzling Picture

• Abstract
• 1 Introduction
• 2 Experiments
• 3 Simulations
• 4 Discussion and Conclusions

Chapter Six: Bicontinuous Phases of Lyotropic Liquid Crystals

• Abstract
• 1 Introduction
• 2 The Model and the Computational Method
• 3 Cubic Phases of Lyotropic Liquid Crystals
• 4 The Structure of the Interface Between the Cubic Phase and the Isotropic Phase
• 5 Conclusions
• Acknowledgments

Chapter Seven: Peculiarities in the Study of Preformed DSPC Lipid Vesicles by Coarse Grain Molecular Dynamics

• Abstract
• 1 Introduction
• 2 Methods and Systems
• 3 Results and Discussion
• 4 Conclusions
• Acknowledgments

Chapter Eight: Extracellular Vesicles in Cancer

• Abstract
• 1 Introduction
• 2 Heterogeneous Forms of Extracellular miRNAs
• 3 Mechanisms of EV Biogenesis, Cargo Sorting, and Secretion
• 4 Methods for Isolation of EVs
• 5 EVs for Discard of Unnecessary miRNAs
• 6 EVs for Proangiogenesis
• 7 EVs as Drug Delivery System for RNAi
• 8 Conclusion and Perspectives
• Acknowledgments

The Elsevier book series Advances in Biomembranes and Lipid Self-Assembly (previously titled Advances in Planar Lipid Bilayers and Liposomes), provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes, and lipid self-assemblies from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature and find their application in the formulation of biomimetic model membranes and in the design of artificial dispersion of liposomes.

Moreover, lipids self-assemble into a wide range of other structures including micelles and the liquid crystalline hexagonal and cubic phases. Consensus has been reached that curved membrane phases do play an important role in nature as well, especially in dynamic processes such as vesicles fusion and cell communication. Self-assembled lipid structures have enormous potential as dynamic materials ranging from artificial lipid membranes to cell membranes, from biosensing to controlled drug delivery, from pharmaceutical formulations to novel food products to mention a few. An assortment of chapters in this volume represents both original research as well as comprehensive reviews written by world leading experts and young researchers.

• Surveys recent theoretical and experimental results on lipid micro- and nanostructures
• Presents potential uses of applications like clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering, and food products
• Provides both original research as well as comprehensive reviews written by world leading experts and young researchers
• Provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes, and lipid self-assemblies from the micro- to the nanoscale.

experts in the field of chemistry, physics and biology of lipid micro- and nano- structures and biological membranes, and a podium for non-specialists working on the interdisciplinary front