Description

Enantioselective synthetic methods are not only in the forefront of chemical and pharmaceutical research but activity in this area is constantly increasing. It is stimulated by the urgency to obtain drugs or compounds of medicinal interest as single anantiomers, and the keeness to synthesize natural products in nonracemic form. This volume presents seven chapters from pioneers and authorities in this rapidly expanding field.

Readership

For scientists and researchers in the field of asymmetric synthesis.

Table of Contents

Preface (A. Hassner). Asymmetric synthesis of &Bgr;-amino acids and &Bgr;-lactum derivatives via cunjugate addition of metal amides (Y. Yamamoto et al.). Enantioselective deprotonation of cyclic ketones (M. Majewski). Stereoselective addition of chiral &agr;-aminoorganometallics to aldehydes (R.E. Gawley). Asymmetric access to functional, structurally diverse molecules exploiting five-membered heterocyclic silyloxy dienes (G. Casiraghi et al.). Asymmetric catalysis using heterobimetallic compounds (M. Shibasaki, H. Sasai). Palladium-catalyzed enantioselective allylic substitution reactions (S.J. Sesay, J.M.J. Williams). New achievements in asymmetric synthesis of organophosphorous compounds (O.I. Kolodiazhnyi).

Details

No. of pages:
364
Language:
English
Copyright:
© 1999
Published:
Imprint:
JAI Press
Print ISBN:
9780762301065
Electronic ISBN:
9780080551999