1. What are Free Radicals?
General Aspects of Free Radicals.
-Aspects of free radicals.
-Types of free radicals.
-Reaction style of radicals.
-Orientation in radical additions.
-Reactivity in radical additions.
-Reaction patterns of radicals.
-Generation of radicals.
Familiar and Close Radicals in Our Lives.
Stable Free Radicals.
Physical and Chemical Characteristics of Free Radicals.
-Orbital interactions between radicals and olefins.
-Rate constants in radical reactions.
2. Functional Group Conversion
Radical Coupling Reactions.
Conversion to Hydroxy Group and Other Functional Groups.
3. Intramolecular Radical Cyclizations
Cyclization to Small-Sized Rings.
-Cyclization onto olefinic group and acetylenic group by sp3 carbon-centered radicals.
-Cyclization onto Olefinic Group and Aromatic Group by sp2 Carbon-Centered Radicals.
-Generation of sp carbon-centered radicals.
-Cyclization onto carbonyl group by sp3 or sp2 carbon-centered radicals and other related cyclizations.
Cyclization to Medium-Sized and Large-Sized Rings.
Cyclization to Spiro Skeleton.
Tandem Cyclization to Polycyclic Rings.
4. Intermolecular Radical Addition Reactions
Addition to Olefins.