Clinical Aspects and Treatment with Isotonic Sodium Bicarbonate Solution

1st Edition - January 1, 1946

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  • Author: Esben Kirk
  • eBook ISBN: 9781483226545

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Acidosis: Clinical Aspects and Treatment with Isotonic Sodium Bicarbonate provides a connected exposition for the use of hospital physicians and general practitioners of the clinical aspect and treatment of acidosis. After briefly dealing with the history of clinical investigation of acidosis and treatment, this five-chapter book goes on discussing the clinical symptoms and form, causes, and complications of acidosis. The next chapter describes the five treatment options for acidosis, including using an isotonic, alkaline, glucose, physiological sodium chloride solutions and alkalosis. Other chapters examine acidosis under physiological and pathological conditions. The concluding chapter surveys the micro- and macro-techniques, as well as Van Slyke's apparatus for bicarbonate content determination of the plasma or the serum. This book will prove useful to clinicians, gastrologists, and general medical practitioners.

Table of Contents

  • Brief Survey of the History of Acidosis and Its Treatment

    I. Introduction

    1. Definition of the Term Acidosis

    2. The Clinical Symptoms of Acidosis

    3. Causes of Acidosis

    4. The Neutrality Regulation of the Organism

    5. Review of the Clinical Forms of Acidosis

    6. Complications of Acidosis: Dehydration, Salt Deficiency and Uremia

    II. The Treatment of Acidosis

    A. Treatment with Isotonic Sodium Bicarbonate Solution

    1. Indications

    2. Forms of Administration

    3. The Preparation of Isotonic Sodium Bicarbonate Solutions

    4. Dosage of Sodium Bicarbonate

    5. Therapeutic Technique

    6. Special Precautions in the Treatment of Renal Acidosis

    7. The Treatment of Acidosis with Bicarbonate Powders and Tablets

    8. Effect of the Administration of Bicarbonate

    9. Secondary Effects of the Treatment. Overdosing

    B. The Use of other Alkaline Solutions for the Treatment of Acidosis

    C. The Treatment of Acidosis with Glucose Solution

    D. Remarks on the Treatment of Acidosis with Physiological Sodium Chloride Solution

    E. Alkalosis

    III. Acidosis under Physiological Conditions

    Lactic Acid Acidosis during Physical Work

    IV. Acidosis under Pathological Conditions

    A. Acidosis due to Uncomplicated Loss of Alkali

    1. Fistula of the small Intestine

    2. Biliary Fistula

    3. Bile Drainage

    4. Pancreatic Fistula

    B. Acidosis due to Loss of Alkali Complicated with Infection and Intoxication

    1. Cholera

    2. Other Severe Diarrheas in Adults (Dysentery, Meat Poisoning, Fungal Poisoning)

    3. Acute Gastro-Enteritis in Children

    C. Acidosis due to Persistent Anacid Vomiting

    1. Hyperemesis gravidarum

    2. Anorexia nervosa

    D. Acidosis caused by an Abnormal Production of Acid

    1. Diabetes mellitus

    2. Ketonemic Vomiting in Children

    3. Inanition Acidosis

    4. Acidosis in Anoxemic Conditions (Cardiac Decompensation, Peripheral circulatory Insufficiency, Severe Anemias)

    5. Acidosis in Anesthesia

    E. Acidosis as a Consequence of Inhibition of the Tissue Oxidation (Inhibition of the Intermediary Metabolism)

    Lactic Acid Acidosis in Guanidine Intoxication

    F. Acidosis due to Acid Retention (and Loss of Total Base)

    1. Acute Nephritis

    2. Nephritis in Mercuric Chloride Poisoning

    3. Nephritis in the Eclampsia of Pregnancy

    4. Chronic Nephritis

    5. Renal Amyloidosis

    6. Prostatic Hypertrophy

    7. Other Surgical Urinary Diseases

    G. Acidosis due to Abnormal Intake of Acid

    1. Sulphuric and Hydrochloric Acid Poisoning

    2. Medicamental Acidosis

    H. Acidosis in Various Other Intoxications

    1. Salicylic Acid Poisoning

    2. Methyl Salicylate Poisoning

    3. Aspirine Poisoning

    4. Methyl Alcohol Poisoning

    5. Methyl Chloride Poisoning

    J. Other Forms of Acidosis not yet fully elucidated

    1. Liver Insufficiency

    2. Acute Febrile Affections of the Bile Ducts and the Liver

    3. Acidosis in Thyreotoxicosis

    4. Acidosis in Acute Suppurative Otitis Media in Infants

    5. Acidosis in Other Serious Infections and Septic Conditions

    K. Premortal Acidosis

    L. Chronic Acidosis

    1. Renal Rickets

    2. Renal Osteomalacia

    3. Osteomalacia following Prolonged Ingestion of Acidotic Drugs

    4. Osteoporosis in Persistent Hepatic Fistulas

    V. Technique for the Determination of the Bicarbonate Content of the Plasma or the Serum

    1. Instructions for Use of Van Slyke's Apparatus

    2. Macro-method for the Determination of the Bicarbonate Content of Serum or Plasma according to the Method of Van Slyke and Neill

    3. Micro-method for the Determination of the Bicarbonate Content of Serum or Plasma according to the Method of Van Slyke and Neill

    Index of Case Records



Product details

  • No. of pages: 226
  • Language: English
  • Copyright: © Butterworth-Heinemann 2013
  • Published: January 1, 1946
  • Imprint: Butterworth-Heinemann
  • eBook ISBN: 9781483226545

About the Author

Esben Kirk

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