A Clinical Guide to Inositols

A Clinical Guide to Inositols

1st Edition - January 15, 2023

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  • Editors: Vittorio Unfer, Didier Dewailly
  • Paperback ISBN: 9780323916738

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A growing body of research demonstrates the potential benefits of the administration of inositol isomers in the treatment of many different disorders, from reproductive to metabolic diseases.A Clinical Guide to Inositols discusses scientific evidence of inositol-based treatments in different clinical fields to provide clinicians with a practical guide to use inositol supplementation within pathological conditions. Each chapter covers a specific disorder and describes aspects of the application of inositol in clinical practice, discussing the physio-pathologic features of the health condition and scientific evidences of the effects of inositol treatment.This book is a valuable resource to researchers and clinicians looking for a clear understanding of clinical effects of inositol supplementation and a practical guide on inositol-based treatments.

Key Features

  • Covers basic knowledge about the biochemistry and physiology of inositol and their pharmacological targets and metabolites
  • Discusses scientific evidence of the benefits of inositol supplementation for the clinical management of different diseases
  • Addresses inositol application from the gynecological and obstetrical field to, among others, the metabolic, fetal, andrological, endocrine, and oncological fields


Researchers, graduate students, and fellows in the fields of endocrinology and gynecology

Table of Contents

  • 1. Introducing inositols and their clinical targets: physiology and pathophysiology
    2. Effectiveness of Myo- and D-chiro-inositol in the treatment of metabolic disorders
    3. Treating PCOS with inositols: choosing the most appropriate myo- to D-chiro-inositol ratio
    4. Overcoming inositol-resistance
    5. Inositol supplementation for preventing Gestational Diabetes Mellitus
    6. Inositol efficacy on the incidence of adverse fetal outcomes
    7. Treatments with inositols in the IVF procedures
    8. Supplementation with D-chiro-inositol in women
    9. Application of myo-inositol and D-chiro-inositol in andrological issues
    10. Myo-inositol supplementation for subclinical hypothyroidism
    11. Respiratory distress and treatment with Myo-inositol to reduce pulmonary inflammation
    12. Inositols as adjuvant treatments in oncology
    13. Myo-inositol supplementation restores inositol depletion induced by treatments for psychiatric and neurological conditions

Product details

  • No. of pages: 300
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: January 15, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780323916738

About the Editors

Vittorio Unfer

Vittorio Unfer, MD, is a Professor at the Faculty of Medicine of the University of Modena and Reggio Emilia, Italy, and also works as an Obstetrics and Gynecology specialist, researcher and university lecturer. His research interests include aspects of nutrition and use of food supplements in obstetrics and gynecology clinical practice and the morphofunctional study of uterine contractile activity with previous uterine scar, the triggering mechanisms of labor, the treatment of the threatened miscarriage abortion and prevention of preterm labor in high-risk patients, the treatment of hypogonadotropic male hypogonadism with FSH, and several in-depth and comparative experimentations on the fetal maturity. Prof. Unfer was one of the first researchers studying the use of myo-inositol in the treatment for polycystic ovary syndrome; his in-depth research pointed out the beneficial effects of the myo-inositol molecule on ovarian function and metabolic parameters. He has published numerous articles in reputed journals, including Fertility and Sterility and International Journal of Molecular Sciences.

Affiliations and Expertise

Professor, University of Modena and Reggio Emilia, Italy

Didier Dewailly

Dr Didier Dewailly is professor of Endocrinology and Reproductive Medicine in the Lille University Hospital, France. Until 2017, he was head of the Department of Endocrine Gynecology and Reproductive Medicine at the Hôpital Jeanne de Flandre, including an IVF unit. He is now retired from the Hospital, but he still keeps an academic position and coordinates the teaching of Medical Gynecology and Reproductive Medicine for the North-West area of France. He is redactor-in-chief of Médecine-Thérapeutique/Médecine de la Reproduction which is the journal of the French Reproductive Medicine Society whom he is past-President. His main fields of interest in research currently are the female hyperandrogenism (Polycystic Ovary Syndrome (PCOS) and other causes) and Ovulation Disorders such as PCOS, hypothalamic amenorrhea, hypogonadotropic hypogonadism and premature ovarian failure.

Affiliations and Expertise

Professor, Endocrinology, Reproductive Medicine, Lille University Hospital, France

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