Transporters in Drug Discovery and Development
Detailed Concepts and Best Practice
- Yurong Lai, A major US pharmaceutical company, USA
Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments.
Scientists working in biopharmaceutical science, drug discovery/development in understanding the principles and techniques for testing drug candidates