- Gerald Combs, Jr., Professor Emeritus, Division of Nutritional Sciences, Cornell University, Ithaca, New York, U.S.A.
The fourth edition of this bestselling text will again provide the latest coverage of the biochemistry and physiology of vitamins and vitamin-like substances. Extensively revised and expanded on the basis of recent research findings with enlarged coverage of health effects of vitamin-like factors, it is ideally suited for students and an important reference for anyone interested in nutrition, food science, animal science or endocrinology. It contains a cohesive and well-organized presentation of each of the vitamins, as well as the history of their discoveries and current information about their roles in nutrition and health.
Hardbound, 598 Pages
Published: December 2012
Imprint: Academic Press
PRAISE FOR THE FIRST EDITION: "It was a pleasure to read this magnificent book that can be used for teaching and as a desk reference. In short, this is the premier textbook in vitamins and may be used at both the graduate and undergraduate levels." -JOURNAL OF OPTIMAL NUTRITION "This text would be useful for anyone teaching a course about vitamins." -FOOD TECHNOLOGY "The organization of the book is a unique and useful approach to presenting material. Students will find the formatting of individual chapters extremely useful. This is an excellent learning textbook for an undergraduate or early graduate course on the vitamins." -JOURNAL OF NUTRITION EDUCATION "The book is obviously valuable to those teaching or using information associated with vitamins. I also recommend the book to other teachers as a way of presenting material to students to learn rather than memorize." -JOURNAL OF VETERINARY MEDICAL EDUCATION "The strength of this book is the clear description of the chemistry of each vitamin and related compounds and of the biochemistry and metabolic functions in the body. For those who want to build their knowledge of the vitamins on a chemical and biochemical base, this book will prove excellent." -AUSTRALIAN VETERINARY JOURNAL
- Part I. Perspectives on the Vitamins in Nutrition1. What is a Vitamin?a. Thinking about Vitaminsb. Vitamin: a Revolutionary Conceptc. A Operating Definition of a Vitamind. The Recognized Vitaminse. Study Questions and Exercises2. Discovery of the Vitaminsa. The Emergence of Nutrition as a Scienceb. The Process of Discovery in Nutritional Sciencec. The Empirical Phase of Vitamin Discoveryd. The Experimental Phase of Vitamin Discoverye. The Vitamine Theoryf. Elucidation of the Vitaminsg. Vitamin Terminologyh. Other factors Sometimes Called Vitaminsi. The Modern History of the Vitaminsj. The Impact of the Omics Revolution in Biologyk. Study questions and Exercisesl. Recommended Reading3. Chemical and Physiological Properties of Vitaminsa. Chemical and Physical Properties of Vitaminsb. Vitamin Ac. Vitamin Dd. Vitamin Ee. Vitamin Kf. Vitamin Cg. Thiaminh. Riboflavini. Niacinj. Vitamin B6k. Biotinl. Pantothenic Acidm. Folaten. Vitamin B12o. General Properties of Vitaminsp. Physiological Properties of Vitaminsq. Metabolism of Vitaminsr. Study Questions and Exercisess. Recommended Reading4. Vitamin Deficiencya. The Concept of Vitamin Deficiencyb. The Many Causes of Vitamin Deficiencyc. Clinical Manifestations of Vitamin Deficienciesd. Vitamin Deficiency Diseases: Manifestations of Biochemical Lesionse. Subclinical Vitamin Deficiencyf. Study Questions and Exercisesg. Recommended ReadingPart II. Considering the Individual Vitamins5. Vitamin Aa. Significance of Vitamin Ab. Sources of Vitamin Ac. Absorption of Vitamin Ad. Transport of Vitamin Ae. Metabolism of Vitamin Af. Excretion of Vitamin Ag. Metabolic Functions of Vitamin Ah. Vitamin A Deficiencyi. Vitamin A Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading6. Vitamin Da. Significance of Vitamin Db. Sources of Vitamin Dc. Absorption of Vitamin Dd. Transport of Vitamin De. Metabolism of Vitamin Df. Excretion of Vitamin Dg. Metabolic Functions of Vitamin Dh. Vitamin D Deficiencyi. Vitamin D Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading7. Vitamin Ea. Significance of Vitamin Eb. Sources of Vitamin Ec. Absorption of Vitamin Ed. Transport of Vitamin Ee. Metabolism of Vitamin Ef. Excretion of Vitamin Eg. Metabolic Functions of Vitamin Eh. Vitamin E Deficiencyi. Vitamin E Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading8. Vitamin Ka. Significance of Vitamin Kb. Sources of Vitamin Kc. Absorption of Vitamin Kd. Transport of Vitamin Ke. Metabolism of Vitamin Kf. Excretion of Vitamin Kg. Metabolic Functions of Vitamin Kh. Vitamin K Deficiencyi. Vitamin K Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading9. Vitamin Ca. Significance of Vitamin Cb. Sources of Vitamin Cc. Absorption of Vitamin Cd. Transport of Vitamin Ce. Metabolism of Vitamin Cf. Excretion of Vitamin Cg. Metabolic Functions of Vitamin Ch. Vitamin C Deficiencyi. Vitamin C Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading10. Thiamina. Significance of Thiaminb. Sources of Thiaminc. Absorption of Thiamind. Transport of Thiamine. Metabolism of Thiaminf. Excretion of Thiaming. Metabolic Functions of Thiaminh. Thiamin Deficiencyi. Thiamin Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading11. Riboflavina. Significance of Riboflavinb. Sources of Riboflavinc. Absorption of Riboflavind. Transport of Riboflavine. Metabolism of Riboflavinf. Excretion of Riboflaving. Metabolic Functions of Riboflavinh. Riboflavin Deficiencyi. Riboflavin Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading12. Niacina. Significance of Niacinb. Sources of Niacinc. Absorption of Niacind. Transport of Niacine. Metabolism of Niacinf. Excretion of Niacing. Metabolic Functions of Niacinh. Niacin Deficiencyi. Pharmacological Uses of Niacinj. Niacin Toxicityk. Case studiesl. Case Questionsm. Study Questions and Exercisesn. Recommended Reading13. Vitamin B6a. Significance of Vitamin B6b. Sources of Vitamin B6c. Absorption of Vitamin B6d. Transport of Vitamin B6e. Metabolism of Vitamin B6f. Excretion of Vitamin B6g. Metabolic Functions of Vitamin B6h. Vitamin B6 Deficiencyi. Pharmacological Uses of Vitamin B6j. Vitamin B6 Toxicityk. Case studiesl. Case Questionsm. Study Questions and Exercisesn. Recommended Reading14. Biotina. Significance of Biotinb. Sources of Biotinc. Absorption of Biotind. Transport of Biotine. Metabolism of Biotinf. Excretion of Bioting. Metabolic Functions of Biotinh. Biotin Deficiencyi. Biotin Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading15. Pantothenic Acida. Significance of Pantothenic Acidb. Sources of Pantothenic Acidc. Absorption of Pantothenic Acidd. Transport of Pantothenic Acide. Metabolism of Pantothenic Acidf. Excretion of Pantothenic Acidg. Metabolic Functions of Pantothenic Acidh. Pantothenic Acid Deficiencyi. Pantothenic Acid Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading16. Folatea. Significance of Folateb. Sources of Folatec. Absorption of Folated. Transport of Folatee. Metabolism of Folatef. Excretion of Folateg. Metabolic Functions of Folateh. Folate Deficiencyi. Folate Toxicityj. Case studiesk. Case Questionsl. Study Questions and Exercisesm. Recommended Reading17. Vitamin B12a. Significance of Vitamin B12b. Sources of Vitamin B12c. Absorption of Vitamin B12d. Transport of Vitamin B12e. Metabolism of Vitamin B12f. Excretion of Vitamin B12g. Metabolic Functions of Vitamin B12h. Vitamin B12 Deficiencyi. Pharmacological Uses of Vitamin B12j. Vitamin B12 Toxicityk. Case studiesl. Case Questionsm. Study Questions and Exercisesn. Recommended Reading18. Quasi-Vitaminsa. Is the Vitamin List Complete?b. Cholinec. Carnitined. Myo-Inositole. Pyrrolyquinoline Quinonef. Ubiquinonesg. Orotic Acidh. Bioflavonoidsi. P-Aminobenzoic acidj. Lipoic Acidk. Inneffective Factorsl. Unidentified Growth Factorsm. Study Questions and Exercisesn. Recommended ReadingPart III. Using Current Knowledge of the Vitamins19. Sources of Vitaminsa. Vitamins in Foodsb. Vitamins in Feedstuffsc. Predicting Vitamin Contentsd. Vitamin Bioavailabilitye. Vitamin Lossesf. Vitamin Supplementation and Fortificationg. Vitamin Labeling of Foodsh. Study Questions and Exercisesi. Recommended Reading20. Assessing Vitamin Statusa. General Aspects of Nutritional Assessmentb. Assessment of Vitamin Statusc. Vitamin Status of Healthy Populationsd. Study questions and Exercisese. Recommended Reading21. Quantifying Vitamin Needsa. Dietary Standardsb. Determining Vitamin Standards for Vitaminsc. Factors Affecting Vitamin Needsd. Vitamin Allowances for Humanse. Vitamin Allowances for Animalsf. Study Questions and Exercisesg. Recommended Reading22. Vitamin Safetya. Uses of Vitamins Above Allowance Levelsb. Hazards of Excessive Vitamin Intakesc. Signs of Hypervitaminosesd. Safe Intakes of Vitaminse. Study Questions and Exercisesf. Recommended ReadingAppendices Appendix A Vitamin Terminology: Past and Present Appendix B Original Reports for Case Studies Appendix C A Core of Current Vitamin Research Literature Appendix D Vitamin Contents of Foods Appendix E Vitamin Contents of FeedstuffsIndex