The Unfolded Protein Response and Cellular Stress, Part A book cover

The Unfolded Protein Response and Cellular Stress, Part A

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.


Researchers and students in cell, molecular and developmental biology

Included in series
Methods in Enzymology

Hardbound, 432 Pages

Published: February 2011

Imprint: Academic Press

ISBN: 978-0-12-385116-1


  • Section I: UPR and Cell Stress in Normal and Diseased Cells

    1. The Unfolded Protein Response in Mouse Cerebral Cortex
    2. Nirinjini Naidoo

    3. Immunohistochemical Detection of the Unfolded Protein Response in Atherosclerotic Plaques
    4. Šárka Lhoták and Richard C. Austin

    5. The role of PDI as a survival factor in cardiomyocyte ischemia
    6. Stefano Toldo; Anna Severino; Antonio Abbate; Alfonso Baldi

    7. Measurement of the Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals
    8. Guenther Boden and Salim Merali

    9. Measurement of the unfolded protein response (UPR) in monocytes
    10. Tomás P. Carroll, Catherine M. Greene, and Noel G. McElvaney

    11. Assessment of Endurance Exercise Training in Hepatic Endoplasmic Reticulum (ER) Stress
    12. Natalie Ann Chapados

    13. Discovery approaches to UPR in athero - susceptible endothelium in vivo
    14. Mete Civelek, Elisabetta Manduchi, Gregory Grant, Christian J. Stoeckert Jr, Peter F. Davies

    15. Assessment of endoplasmic reticulum stress and the unfolded protein response in endothelial cells
    16. Ines Witte & Sven Horke

    17. Measuring the impact of cigarette smoke on the UPR
    18. Hong Zhao, Jin Yang, Lin Shan and Ellen D. Jorgensen

    19. Induction and measurement of UPR and osmotic stress in the yeast Pichia pastoris
    20. Martin Dragosits, Diethard Mattanovich and Brigitte Gasser

    21. Induction of ER stress response leading to programmed cell death in Trypanosoma brucei
    22. Hanoch Goldshmidt and Shulamit Michaeli

    23. Measurement of Activation of the Endoplasmic Reticulum Stress Response in Autoimmune Myositis
    24. Heather M. Alger, Sree Rayavarapu and Kanneboyina Nagaraju

    25. Activation of the unfolded protein response in human acute myeloid leukemia
    26. Julian A. Schardt , Beatrice U. Mueller and Thomas Pabst

    27. Modulation of the Unfolded Protein Response by GRP78 in Prostate Cancer
    28. Gustaaf de Ridder, Rupa Ray, Uma K. Misra and Salvatore V. Pizzo

    29. Endoplasmic Reticulum Stress In Brain Damage
    30. Ram Raghubir, Venkata Prasuja Nakka, and Suresh L. Mehta

    31. Methods and Models for Monitoring UPR associated Macrophage Death during Advanced Atherosclerosis
    32. Edward B. Thorp

    33. Detecting Autophagy in Response to ER Stress Signals in Cancer
    34. Guillermo Velasco, María Salazar, Sonia Hernández-Tiedra, Sofía Torres, Mar Lorente, Manuel Guzmán

    35. The Unfolded Protein Response Induced By Salt Stress in Arabidopsis
    36. Miaoying Wang, Qiangyi Xu, and Ming Yuan

    37. Measurement of ER Stress Response and Inflammation in the Mouse Model of Non-alcoholic Fatty Liver Disease

    Ze Zheng , Chunbin Zhang, Kezhong Zhang


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