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The SV40 Replicon Model for Analysis of Anticancer Drugs

  • 1st Edition - April 3, 1996
  • Author: Robert M. Snapka
  • Language: English
  • Hardback ISBN:
    9 7 8 - 0 - 1 2 - 6 5 3 6 3 0 - 0
  • eBook ISBN:
    9 7 8 - 0 - 0 8 - 0 5 5 0 1 8 - 3

This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on… Read more

The SV40 Replicon Model for Analysis of Anticancer Drugs

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This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments.