The Role of Sphingolipids in Cancer Development and Therapy

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "The Role of Sphingolipids in Cancer Development and Therapy"
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Researchers and students in the basic and clinical sciences of cancer biology and oncology, plus related areas in genetics, immunology, pharmacology, cell biology, and molecular biology.


Book information

  • Published: January 2013
  • ISBN: 978-0-12-394274-6

Table of Contents

  1. Therapeutic potential of targeting SK1 in human cancers
    Dmitry Pshezhetskiy
  2. Natural products as platforms for the design of sphingolipid derived anticancer agents
    Gemma Fabrias
  3. Hypoxia, therapeutic resistance and sphingosine 1-phosphate
    Olivier Cuvillier
  4. Use of acid sphingomyelinase for cancer therapy
    Edward H. Schuchman
  5. Diverse functions of ceramide on cancer cell death and proliferation
    Besim Ogretmen
  6. Sphingosine kinase and cancer
    Lina M. Obeid
  7. Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance
    Yong-Yu Liu
  8. Interdiction of sphingolipid metabolism to improve standard of care cancer therapies
    James S. Norris