The Pituitary book cover

The Pituitary

Third Edition

The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary.

The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing.

The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy.

Audience

Endocrinologists and researchers of endocrine diseases across biomedical disciplines, as well as those working with endocrinologists such as neurosurgeons and OB/GYNs.

Hardbound, 744 Pages

Published: December 2010

Imprint: Academic Press

ISBN: 978-0-12-380926-1

Reviews

  • "…the book is not only a must for scientists and clinicians usually involved in the management of neuroendocrine dysfunctions but also a great opportunity for other specialists (internists, pediatricians, gynecologists, neurosurgeons) as well as for medical students to familiarize at best with the pituitary and its disorders. In all, this book is a traditional masterpiece dedicated to the ‘‘master gland’’ by one of the most important opinion leaders in the field."--Endocrine 2012 vol.41 p.159

    "[T]he book provides the reader a unique opportunity to understand in depth the mechanisms subserving both normal and disordered pituitary hormone secretion and action. Thus, the book is not only a must for scientists and clinicians usually involved in the management of neuroendocrine dysfunctions but also a great opportunity for other specialists (internists, pediatricians, gynecologists, neurosurgeons) as well as for medical students to familiarize at best with the pituitary and its disorders. In all, this book is a traditional masterpiece dedicated to the ‘‘master gland’’ by one of the most important opinion leaders in the field."--Endocrine

    SECOND EDITION:

    "This excellent second edition is an update of the highly successful first edition of The Pituitary, published in 1995…All the chapters were written by leading experts in the field; a particularly welcome addition is a chapter dedicated to pituitary surgery, by Fahlbusch and colleagues. All the chapters have been successfully updated, and all are comprehensively referenced. The new edition describes recent developments in medical therapies for acromegaly (and thyrotropin-producing adenomas), especially the role of long-acting forms of somatostatin analogues and new growth hormone-receptor antagonists, as well as newer and more effective dopamine agonists for patients with prolactinoma. Inevitably, availability and licensing are subject to worldwide variations and differences in therapeutic practice. Not all the chapters recognize the differences between the United States and other parts of the world, especially Europe, in the availability of therapies that can be offered to patients with pituitary disease. The chapter on hypopituitarism does not fully address the various ways we can now deliver androgen replacement (and their pros and cons) and still mentions the use of extracts of animal thyroids in managing thyrotropin deficiency. There is an extensive discussion of growth hormone deficiency and its treatment with recombinant human growth hormone, but the sensitive and clinically critical issue of whether this expensive therapy should be prescribed for all adults with growth hormone deficiency or only for selected subgroups is avoided. These minor points should not detract from the view that this is a truly excellent book. It is clearly written, and nearly all of it is easy to read. I believe it is an essential and important textbook for practicing endocrinologists and endocrine scientists, trainees in endocrinology, and those working with endocrinologists in the care of patients with pituitary disease, including pediatricians, surgeons, radiologists, oncologists, and endocrine biochemists. It is a fitting tribute, indeed, to the gland that represents the "conductor of the endocrine orchestra."--The New England Journal of Medicine

    FIRST EDITION:

    "I strongly recommend this book. It fills a void in literature by providing in-depth coverage of the pituitary. The book will serve endocrinologists as a source of information on the various aspects of pituitary disease, blending clinical and basic science into a cohesive and comprehensive story."-- New England Journal of Medicine, December 1995

    "The depth of treatment is impressive throughout and all chapters are highly readable…this book is well worth its price."-- Journal of Neurosurgery, January 1996


Contents

  • Section 1 Hypothalamic-Pituitary Function

    1. Functional Anatomy of the Hypothalamic Pituitary Axis

    Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles

    2. Adrenocorticotropin

    Mark A. Herman, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas

    Joseph A. Majzoub, Children’s Hospital, Harvard Medical School, Division of Endocrinology, Boston

    3. Growth Hormone

    Vivien S. Herman-Bonert, UCLA School of Medicine, Division of Endocrinology, Los Angeles

    Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles

    4. Prolactin

    Mark E. Molitch, Northwestern University Medical School, Center for Endocrinology, Metabolism, and Molecular Medicine

    5. Thyroid-stimulating Hormone

    Chester E. Ridgway, University of Colorado Health Sciences Center, Division of Endocrinology

    6. Follicle-stimulating Hormone and Leutinizing Hormone

    Ronald S. Swerdloff, Harbor/UCLA Medical Center, UCLA School of Medicine, Division of Endocrinology

    Shalender Bhasin, Drew University School of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine

    7. The Posterior Pituitary

    Daniel G. Bichet, University of Montreal, Department of Medicine, Montreal

    Section 2 Hypothalamic-Pituitary Dysfunction

    8. The Hypothalamus

    Glenn D. Braunstein, Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles

    9. Anterior Pituitary Failure

    Charles F. Abboud, Mayo Clinic, Mayo Medical School, Rochester

    Sect. 3 Pituitary Tumors

    10. Pituitary Surgery

    Rudolf Fahlbusch, Professor of Neurosurgery, University of Erlangen-Nurnberg, Germany

    11. Radiation and Non-surgical Management of the Pituitary

    Laurence Katznelson, Stanford University School of Medicine, Department of Neurosurgery, Stanford

    12. Acromegaly

    Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles

    13. Prolactinoma

    Mark E. Molitch, Northwestern University Medical School, Center for Endocrinology, Metabolism, and Molecular Medicine

    14. Cushing's Disease

    Lynn Loriaux , Oregon Health & Science University, Chair, Department of Medicine, Portland

    Jean–Pierre Luton, Professor of Endocrinology, Cochin Medical School, University Rene Decartes, Paris, France

    15. Thyrotropin-secreting Pituitary Tumors

    Shlomo Melmed, Cedars-Sinai Medical Center, Los Angeles

    16. Gonadotroph Adenomas

    Margaret E. Wierman, University of Colorado Health Sciences Center, Division of Endocrinology, Denver

    Peter J. Snyder, University of Pennsylvania School of Medicine, Philadelphia

    17. Other Piuitary Lesions

    Stephen A. Geller, UCLA, School of Medicine, Los Angeles

    Section 4 Pituitary Disease in Systemic Disorders

    18. Pituitary Function in Systemic Disorders

    William F. Chandler, University of Michigan, Pituitary and Neuroendocrine Center, Ann Arbor

    19. The Pituitary Gland in Pregnancy and the Puerperium

    Errol R. Norwitz, Yale University School of Medicine, Division of Maternal-Fetal Medicine, New Haven

    20. Drugs and Pituitary Function

    Elizabeth Ginsberg, Brigham and Women’s Hospital, Harvard University Medical School

    Section 5 Diagnostic Procedures

    21. Pituitary Imaging

    Barry D. Pressman, Cedars-Sinai Medical Center, Chief, Section of Neuroradiology and Chairman, Department of Imaging, Los Angeles

    22. Neuro-ophthalmologic Evaluation of Pituitary Disorders

    Anthony C. Arnold, UCLA, Department of Opthalmology, Los Angeles

    23. Evaluation of Normal Pituitary Function

    Gillian L. Booth, Department of Medicine, University of Toronto, Canada

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