The Guide to Investigation of Mouse Pregnancy

Edited by

  • B. Anne Croy, Dept. of Biomedical and Molecular Sciences, School of Medicine, Queen's University, ON, Canada
  • Aureo Yamada, Instituto de Biologia, Universidade Estadual de Campinas, Campinas, Brazil
  • Francesco DeMayo, Developmental Biology, Baylor College of Medicine,TX, U.S.A.
  • S. Lee Adamson, Samuel Lunenfeld Research Institute of Mount Sinai Hospital,ON,Canada

The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells.

Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research.

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This book is intended for basic scientists and clinical investigators researching reproduction, immunology, developmental biology, cardiology, gynecology, animal care, and veterinary medicine; graduate students; postdocs; veterinary technologists; and laboratory technologists.


Book information

  • Published: January 2014
  • ISBN: 978-0-12-394445-0


"The editors must be congratulated with this book, which will be extremely useful to all investigators who are focussing on this most popular animal model."--Placenta, November 28, 2014

"The text is clear and concise and contains something for beginning and expert investigators alike...This book will be a valued addition to the library of any pregnancy researcher who uses mice as their model organism."--Journal of the American Veterinary Medical Association, 15-Sep-14

Table of Contents

Part I. Atlas of Figure Plates
Part II. Basic Biology
Part IIA. Estrus, Early Development, Implantation and Uterine Receptivity
Part IIB. The Maternal-Fetal Interface 
Part IIC. Parturition, lactation, postnatal behaviors and outcomes
Part III. Protocols for Studies of the Placenta and Pregnancy in Mice
Appendix 1. Reproductive performance in common strains of mice