Textbook of Nephro-Endocrinology

Edited by

  • Ajay Singh, MB, FRCP, Clinical Chief, Renal Division, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School, Cambridge, MA, USA
  • Gordon Williams, Director, Center for Clinical Investigation, Brigham and Women's Hospital, Professor of Medicine, Harvard Medical School, Cambridge, MA, USA

The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism.
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Researchers and clinicians in nephrology and endocrinology.


Book information

  • Published: December 2008
  • ISBN: 978-0-12-373870-7


"This well-written, relatively concise, and current book will find a home on the shelves of many nephrologists and endocrinologists. Because it is so readable, it should be useful for students, experts, and those in between. I know I will consult my copy on a frequent basis - an unusual event in this era of online material."
-- As reviewed in N Engl J Med 2009; 361: 832

"All in all, this is a solid book that provides substantial up-todate information on endocrine aspects of the kidney. I will be glad to pull it down from my shelf rather than one of the true heavyweights to which I would previously have gone for this kind of reading."
-- Kidney International (2009)

“Written by multidisciplinary experts from several countries, this book is divided into 2 parts and 7 sections. A very useful volume. Each chapter is richly referenced.”
-- Zvi Laron, Pediatric Endocrinology Reviews

Table of Contents

Part 1: The Kidney as an Endocrine OrganSection 1: Erythropoietin 1.Erythropoientin: An Historical Overview of Physiology, Molecular BiologyAnd Gene Regulation David R. Mole, Peter J. Ratcliffe 2.Erythropoiesis: The Role of Erythropoietin and IronHerbert Lin 3.Extra-Hematopoietic Action of ErythropoietinZheqing Cai, Gregg Semenza 4.Development of Recombinant Erythropoietin and Erythropoietin AnaloguesIain Macdougall 5.Erythropoietin Disease States & ResistanceAjay K. Singh, Tejas Patel, Shona Pendse, Sairam Keithi-Reddy Section 2: Vitamin D, PTH and Novel Regulators of Phosphate6.Vitamin D and the Kidney: Introduction and Historical PerspectiveAjay K. Singh, Tejas Patel 7. Vitamin D: Molecular Biology and Gene RegulationAdriana Dusso, Alex J. Brown 8. Molecular Biology of Parathyroid Hormone Peter A. Friedman 9.Endocrine Regulation of Phosphate HomeostasisHarald Jüppner Section 3: Renin-angiotensin 10.Introduction and Historical OverviewJoel Menard 11.Molecular Biology of Renin and Regulation of Its GeneTimothy L. Reudelhuber, Daniel F. Catanzaro 12. Physiology and Regulation of the RAAS SystemRobert Carey, Shetal H. Padia 13. The Renin Angiotensin Aldosterone System and the KidneyGeorge Bakris, Benjamin Ko 14. The Renin Angiotensin and the Heart Carlos Ferrario, Aaron Trask 15. The Renin-Angrotensin blockade: Therapeutic Agents Domenic Sica Part 2: The Kidney as a Hormonal targetSection 4: Anti-diuretic Hormone 16. Vasopressin in the Kidney: Historical AspectsJeffrey Sands, Lynn E. Schlanger 17. Molecular Biology and Gene RegulationCarolyn Ecelbarger, Swasti Tiwari 18. Vasopressin Antagonists in Physiology and Disease Tomas Berl, Robert W. Schrier 19. Diabetes Insipidus and SIADH J Carlos Ayus, Michael Moritz Section 5: The Atrial Natriuretic Peptides 20. ANP, BNP and CNP Physiology and Pharmacology of the Cardiorenal AxisJohn C Burnett, Jr., Candace Lee Section 6: Aldosterone 21.Introduction and Historical OverviewJohn Coghlan, James Tait 22.Aldosterone Receptors and Their Renal Effects: Molecular Biology And Gene RegulationCelso Gomez-Sanchez, Elise P. Gomez-Sanchez, Mario Galigniana 23. Aldosterone and Its Cardiovascular EffectsGail K Adler, Rajesh Garg 24. Aldosterone RegulationWilliam Rainey, Wendy B. Bollag, Carlos M. Isales Section 7: Endocrine Disorders in Renal Failure25. Insulin resistance Donald Simonson 26. Growth hormone John Mahan 27.Sexual Dysfunction in Men and Women with Chronic Kidney Disease Biff F. Palmer 28.Thyroid Status in Chronic Renal Failure Patients Victoria Lim, Manish Suneja 29.Metabolic Acidosis of Chronic Kidney Disease Jeffrey A. Kraut, Glenn T. Nagami 30.Pregnancy and the Kidney Ananth Karumanchi, Chun Lam