Chemicals Which Cause Birth Defects

Edited by

  • V.M. Kolb, University of Wisconsin, Kenosha, WI, USA

This second revised edition deals with the practical aspect of teratogens - chemicals which cause birth defects. It covers such issues as how to obtain information about the teratogenic potential of chemicals, and includes a list of 5,625 names of chemicals associated with reproductive effects. The book also deals with teratogenic chemicals in undergraduate chemistry laboratories; the principles and mechanisms of teratogenesis; biochemical determinants of chemical teratogenesis; the relationship between maternal occupational exposure and spontaneous abortion; the legal and ethical aspects of fetal protection policies; and safe handling of teratogenic chemicals in the laboratory. This volume will be of great interest to chemists and other professionals working with teratogens.
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Book information

  • Published: September 1993
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-81482-1

Table of Contents

Preface. Principles and Mechanisms of Teratogenesis (P.E. Levi). Maternal Occupational Exposure and Spontaneous Abortion (M.L. Lindbohm). Biochemical Determinants of Chemical Teratogenesis: Studies with Phenytoin, Benzo(a)pyrene and Related Xenobiotics (P.G. Wells). Legal and Ethical Aspects of Fetal Protection Policies (S.M. Norton). Teratogenic Chemicals in Undergraduate Chemistry Laboratories (D.K. Kolb). How to Obtain Information about the Teratogenic Potential of Chemicals (J.S. Wassom et al.). Registry of Toxic Effects of Chemical Substances as a Source for Compiling a List of Teratogens (V. Kolb). List of chemicals from RTECs which cause reproductive effects. Safe Handling of Teratogenic Chemicals in the Laboratory (V. Kolb). Subject Index.