Surface Modification of Biomaterials book cover

Surface Modification of Biomaterials

Methods Analysis and Applications

The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material’s surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance.

Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone.

The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification.

Hardbound, 432 Pages

Published: November 2010

Imprint: Woodhead Publishing

ISBN: 978-1-84569-640-5

Contents

  • Part 1 Surface modification techniques: Surface modification of biomaterials by plasma polymerisation; Surface modification of biomaterials by covalent binding of poly(ethylene glycol) (PEG); Surface modification of biomaterials by heparinisation to improve blood compatibility; Surface modification of biomaterials by peptide functionalisation; Metal surface oxidation and surface interactions; Surface modification of biomaterials by calcium phosphate deposition; Biomaterial surface topography to control cellular response: Technologies, cell behaviour and biomedical applications. Part 2 Analytical techniques and applications: Techniques for analysing biomaterial surface chemistry; Techniques for analysing biomaterial surface structure, morphology and topography; Modifying biomaterial surfaces to optimise interactions with blood; Modifying biomaterials surfaces with bioactives to control infection; Modifying biomaterial surfaces to optimise interactions with soft tissues; Modifying biomaterial surfaces for the repair and regeneration of nerve cells; Modifying biomaterial surfaces to control stem cell growth and differentiation; Modifying biomaterial surfaces to optimise interactions with bone.

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