Stem Cells book cover

Stem Cells

Scientific Facts and Fiction

In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues of which everyone presumed were unable to regenerate in adults; these include particularly the heart and the brain. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson, diabetes and spinal cord lesions based on the use of stem cells and entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies.

As is often the case in science, many early claims turned out to be different from those expected. Embryonic stem cell therapies have not moved rapidly into clinical practice. Adult stem cells certainly have given certain degrees of success but not nearly to the extent that advocates would have wished for. Some claims of early successes in adult stem cell therapies have not been sustained in double-blinded, randomized clinical trials. Some claims are now close to routine therapy. Some of the claims not supported by evidence have nevertheless reached private clinical practice so that "stem cell tourism" is beginning to reach exaggerated proportions.

This book provides the reader background information on stem cells in a clear and well-organized manner. It provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. It distinguishes itself from the multiplicity of websites on the subject of stem cells by being scientifically, politically and ethically neutral, explaining pros and cons for stem cells of every sort with the intention of reaching a wide readership ranging from advanced students and patient advocacy groups to clinicians, specialists and early phase medics in training. By providing the background scientific and social information, it provides readers with the information they require to form their own opinions on the use of stem cells on the basis of facts rather than hype.

Paperback, 324 Pages

Published: November 2010

Imprint: Academic Press

ISBN: 978-0-12-381535-4

Reviews

  • Winner of two British Medical Association 2011 awards: BMA Board of Science Award for the Public Understanding of Science and First Prize in the category of Basic and Clinical Sciences

    "Stem Cells: Scientific Facts and Fiction provides the reader background information on stem cells in a clear and well-organized manner. It provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. It distinguishes itself from the multiplicity of websites on the subject of stem cells by being scientifically, politically and ethically neutral, explaining pros and cons for stem cells of every sort with the intention of reaching a wide readership ranging from advanced students and patient advocacy groups to clinicians, specialists and early phase medics in training. By providing the background scientific and social information, it provides readers with the information they require to form their own opinions on the use of stem cells on the basis of facts rather than hype."--British Medical Association Board of Science Award for the Public Understanding of Science Copy excerpted from BMA website


Contents

  • Foreword 
    Introduction 
    Chapter 1: Biology of the Cell 
    Chapter 2: Embryonic development 
    Chapter 3: Of mice and men: History of stem cells 
    Chapter 4: What are stem cells? 
    Chapter 5: Origin of stem cells 
    Chapter 6: Types of stem cells 
    Chapter 7: Cloning: history and current applications 
    Chapter 8: Clinical applications of stem cells 
    Chapter 9: Cancer stem cells  
    Chapter 10: Applications for drugs and toxicity screening 
    Chapter 11: Venturing in stem cells (law and intellectual property) 
    Chapter 12: Future Prospects 

    References and websites 

    Glossary of terms 

    Index 

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