Side Effects of Drugs Annual

A worldwide yearly survey of new data and trends in adverse drug reactions

Edited by

  • Jeffrey K. Aronson, MA DPhil MBChB FRCP FBPharmacolS FFPM(Hon), Department of Primary Health Care, University of Oxford, Oxford, UK

Volume 28 in the series of Side Effects of Drugs Annuals ( continues to serve its primary goal: to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has reviewed new data and trends by selecting from the year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is unproven or misleading. The use of the book is enhanced by separate indexes, allowing the reader to access the text via drug name, adverse effect, or drug interaction. The current annual includes an essay by the editor, Dr Jeffrey Aronson, entitled 'Classifying Drug Adverse Reactions in the 21st Century.' In it he describes how the modern approach to classifying adverse drug reactions takes into account the dose that causes the reaction, the time-course of the reaction, and the susceptibility factors that increase the individual patient's risk, and shows how this analysis can facilitate regulatory decision making.
View full description


Pharmacologists, clinicians, pharmaceutical companies, clinical toxicologists, Clinical pharmacologists, and medical libraries


Book information

  • Published: November 2005
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-51571-1

Table of Contents

ContributorsCumulative Index of Special ReviewsHow to use this bookEssay Classifying Adverse Drug Reactions in the 21st Century; J.K. Aronson1 Central nervous system stimulants and drugs that suppress appetite, R.P. Sequeira2 Antidepressant drugs P.J. Cowen 3 LithiumD.L. Dunner4 Drugs of abuseJ.K. Patel, Timothy E Ralston, and E.J. wong 5 Hypnotics and sedativesS. Curran and S. Musa6 Antipsychotic drugsA. Carvajal,L.H. Martín Arias and Natalia Jimeno7 Antiepileptic drugsA. Gil-Nagel8 Opioid analgesics and narcotic antagonistsA.H. Ghodse and A.M. Baldacchino9 Anti-inflammatory and antipyretic analgesics and drugs used in goutA. Del Favero10 General anesthetics and therapeutic gasesY. Young11 Local anestheticsS.A. Schug, P. Flisberg, S.A. Jackson, D.J. O’Connnor 12 Neuromuscular blocking agents and skeletal muscle relaxantsO. Zuzan and M. Leuwer13 Drugs that affect autonomic functions or the extrapyramidal systemM. Schachter14 Dermatological drugs and topical agentsS.R. Knowles, G. Wong, N.H. Shear15 Antihistamines (H1 receptor antagonists)G.M. Walsh16 Drugs acting on the respiratory tract M. Joerger, K. Hartmann, and M. Kuhn17 Positive inotropic drugs and drugs used in dysrhythmiasJ.K. Aronson 18 Beta-adrenoceptor antagonists and antianginal drugs A.P. Maggioni, M.G. Franzosi, and R. Latini19 Drugs acting on the cerebral and peripheral circulations R. Verhaeghe20 Antihypertensive drugs P. Joubert21 Diuretics D.A. Sica22 Metals G.B. van der Voet and F.A. de Wolff23 Metal antagonists R.H.B. Meyboom24 Antiseptic drugs and disinfectants P. Magee25 Penicillins, cephalosporins, other beta-lactam antibiotics, and tetracyclinesT. Midtvedt26 Miscellaneous antibacterial drugsA. Imhof 27 Antifungal drugs A.H. Groll, H. Kolve, and T.J. Walsh28 Antiprotozoal drugs J. Buser, K. Fattinger29 Antiviral drugs P.L. Vernazza, P. Schmid30 Drugs used in tuberculosis and leprosy S. Swaminathan31 Antihelminthic drugs P.J.J. van Genderen32 Vaccines S. Dittmann33 Blood, blood components, plasma and plasma products P.J.M. Vossebeld, P. Stangers and W.G. van Aken34 Formulations used in nutritionM.C. Allwood and G. Hardy35 Drugs affecting blood coagulation, fibrinolysis, and hemostasisD. Keeling and J.K. Aronson36 Gastrointestinal drugs S. Dar, H.N. Dalton37 Drugs that act on the immune system: cytokines and monoclonal antibodies T.Vial, J. Descotes, C. Ludwig, and M. Behrend38 Drugs that act on the immune system: immunosuppressive and immunostimulatory drugsF. Braun and M. Behrend39 Corticotrophins, corticosteroids, and prostaglandinsJ. Costa and M. Farré40 Sex hormones and related compounds, including hormonal contraceptives M.N.G. Dukes41 Thyroid hormones iodine, and antithyroid drugs J.A. Franklyn 42 Insulin, glucagon, and hypoglycemic drugs H.M.J. Krans43 Miscellaneous hormones R. Page44 Drugs that affect lipid metabolism I. Aursnes45 Cytostatic drugs Hans-Peter Lipp, Jörg Thomas Hartmann, and Andrew Stanley46 Radiological contrast agents S.K. Morcos 47 Drugs used in ocular treatment B.C.P. Polak48 Treatments used in complementary and alternative medicine E. Ernst49 Miscellaneous drugs and materials, medical devices and techniquesN.H. Choulis and J.K. Aronson