Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

1st Edition - October 24, 2017
Editors: Tahira Farooqui, Akhlaq A. Farooqui
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 1 1 9 5 9 - 4
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 1 1 9 6 0 - 0

Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain… Read more

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

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Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD) and Amyotrophic Lateral Sclerosis (ALS), also providing information on how cardiovascular disease, Type 2 Diabetes, and Metabolic Syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction.

The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline.

1. Effect of Mediterranean diet components on neurodegenerative diseases
Akhlaq A. Farooqui and Tahira Farooqui

2. The Mediterranean diet and healthy brain aging: Innovations from nutritional cognitive neuroscience
Marta K. Zamroziewicz and Aron K. Barbey

3. Molecular and intracellular signaling mechanisms of herbs, spices, and food components in the Mediterranean diet in improving cognitive function
Kiran S. Panickar, Selena K. Tavener and Dennis E. Jewell

4. The molecular bases for protective effect of Mediterranean diet in neurodegenerative disorders
Jai Malik and Sunayna Choudhary

5. Multinutrient approach to slow down brain aging and related neurodegenerative disorders
Abhishek Kumar Singh, Sandeep Singh, Geetika Garg and Syed Ibrahim Rizvi

6. Effect of Mediterranean diet on healthy brain aging: Involvement of telomerase
Virginia Boccardi, Clara Tinarelli and Patrizia Mecocci

7. Mediterranean diet and dementia: Can this be a preventive approach?
Marco Canevelli, Giuseppe Bruno, Nicola Vanacore and Matteo Cesari

8. Effects of dietary components on microglia inactivation in Alzheimer’s disease
Harsharan Singh Bhatia

9. Contribution of Mediterranean diet in the prevention of Alzheimer’s disease
Francesco Panza, Madia Lozupone, Vincenzo Solfrizzi, Carlo Custodero, Vincenzo Valiani, Alessia D'Introno, Roberta Stallone, Eleonora Stella, Marco Piccininni, Antonello Bellomo, Davide Seripa, Antonio Daniele, Antonio Greco and Giancarlo Logroscino

10. Mediterranean diet and its impact on cognitive functions in aging
Kanti Bhooshan Pandey

11. Mediterranean diet and diabetic retinopathy
Mohammad Shamsul Ola and Abdullah S. Alhomida

12. Mediterranean diet as a potential strategy to reduce cognitive decline and dementia in elderly
Alissa Knight

13. Effect of Mediterranean diet components on type 2 diabetes and metabolic syndrome
Akhlaq A. Farooqui and Tahira Farooqui

14. Interactions between age, diet and insulin, and their effect on cognition: Implications for Alzheimer's Disease
Elisa Felix-Soriano, María J. Moreno-Aliaga, María J. Ramirez and Maite Solas

15. The use of polyphenols for the treatment of Alzheimer's Disease
Sethuraman Sathya and Pandima Devi Kasi

16. Neuroprotective effects of garlic in model systems of neurodegenerative diseases
Tahira Farooqui and Akhlaq A. Farooqui

17. Neuroprotective properties of wine: Implications for the prevention of cognitive impairment
Jose Rodríguez-Morató, Anna Boronat, Mara Dierssen and Rafael de la Torre

18. Red wine retards Aβ deposition and neuroinflammation in Alzheimer's disease
Ashish Dhir

19. Contribution of diabetes and metabolic syndrome in the pathogenesis of Alzheimer disease
Akhlaq A. Farooqui and Tahira Farooqui

20. Effects of western, Mediterranean, vegetarian, and Okinawan diet pattern on human brain
Akhlaq A. Farooqui and Tahira Farooqui

21. Mediterranean diet is beneficial: But, how and why?
Undurti N. Das

22. Multi-nutrient intervention in the prevention and treatment of dementia
Blanka Klimova and Kamil Kuca

23. Cardioprotective properties of wine: Implications for the management of neurodegenerative diseases
Anna Boronat, Jose Rodríguez-Morató, Montserrat Fitó and Rafael de la Torre

24. Anti-inflammatory properties of dietary n-3 polyunsaturated fatty acids protect against cognitive decline in aging and neurodegenerative diseases
Agnes Nadjar, Quentin Leyrolle, Corinne Joffre and Sophie Layé

25. Effects of dietary omega-3 fatty acid consumption
Anand A. Zanwar, Asavari Joshi and Mahabaleshwar V. Hegde

26. Interplay between lipid mediators and immune system in the promotion of brain self-repair
Simon C. Dyall

27. Importance of fruit and vegetable-derived flavonoids in the Mediterranean diet: Molecular and pathological aspects.
Akhlaq A. Farooqui and Tahira Farooqui

28. Perspective and directions for future research
Tahira Farooqui and Akhlaq A. Farooqui

Tahira Farooqui

Tahira Farooqui has published extensively on drug receptor interactions, biogenic amines in vertebrate and invertebrate nervous systems, biogenic amines mediated signaling, neural plasticity, as well as neuromoulatory roles of octopamine in the reinorcepathway involved in learning and memory, glycerophospholipid and sphingolipid metabolism and molecular signaling mechanisms in the brain. She is the author of 65 peer-reviewed research articles, one monographs and 8 edited books. She has coauthored a monograph in 2008 Metabolism and Function of Bioactive Ether Lipids in the Brain, 2008, by Springer, and have edited 8 Life Sciences books:1) Biogenic Amines: Pharmacological, Neurochemical, and Molecular Aspects in CNS, 2010, NOVA Science Publishers; 2) Phytochemicals and Human Health: Pharmacological and Molecular Aspects, 2011, NOVA Science Publishers; 3) Molecular Aspects of Neurodegeneration and Neuroprotection, 2011, Bentham Science Publishers; 4) Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Oxidative Stress on Cell Signaling, 2012, John Wiley & Sons, Inc; 5) Beneficial effects of propolis on human health and chronic diseases. Vol I, 2012, NOVA Science Publishers, Hauppage, New York; 6) Tahira Farooqui and Akhlaq A. Farooqui, Beneficial effects of propolis on human health and chronic diseases. Vol II, 2012, NOVA Science Publishers, Hauppage, New York; 7) Metabolic Syndrome and Neurological Disorders, 2013, John Wiley & Sons, Inc.; and 8) Diet and Exercise in Cognitive Function and Neurological Diseases, 2015, John Wiley & Sons, Inc.

Affiliations and expertise

Research Scientist, Department of Entomology/Center for Molecular Neurobiology, College of Biological Sciences, The Ohio State University, Columbus, OH, USA

Akhlaq A. Farooqui

Akhlaq A. Farooqui is a leader in the field of signal transduction processes, lipid mediators, phospholipases, glutamate neurotoxicity, and neurological disorders. He is a research scientist in the Department of Molecular and Cellular Biochemistry at The Ohio State University. He has published cutting edge research on the role of phospholipases A2 in signal transduction processes, generation and identification of lipid mediators during neurodegeneration by lipidomics. He has studied the involvement of glycerophospholipid, sphingolipid-, and cholesterol-derived lipid mediators in kainic acid neurotoxicity, an experimental model of neurodegenerative diseases. Akhlaq A. Farooqui has discovered the stimulation of plasmalogen- selective phospholipase A2 in brains of patients with Alzheimer disease (AD). Stimulation of this enzyme may not only be responsible for the deficiency of plasmalogens in neural membranes of AD patients, but also be related to the loss of synapse in the AD.

Affiliations and expertise

Research Scientist, Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, USA