Research Methods in BIomineralization Science

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in biomineralization science, and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure.
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Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists.


Book information

  • Published: November 2013
  • ISBN: 978-0-12-416617-2

Table of Contents

Determining solution chemistry, structure and nucleation
1. Development of accurate force fields for the simulation of biomineralisation
  Paolo Raiteri, Raffaella Demichelis and Julian D. Gale
2. The integration of ion potentiometric measurements with chemical, structural and morphological analysis to follow mineralization reactions in solution.
  Wouter Habraken
3. Investigating the Early Stages of Mineral Precipitation by Potentiometric Titration and Analytical Ultracentrifugation
  Matthias Kellermeier, Helmut Cölfen, Denis Gebauer
4. Replica Exchange Methods in Biomineral Simulations
  Adam Wallace
5. SAXS in inorganic and bio-inspired research
  Tomasz M. Stawski and Liane G. Benning
6. In situ Solution Study of Calcium Phosphate Crystallization Kinetics
  Haihua Pan, Shuqin Jiang, Tianlan Zhang and Ruikang Tang

Probing structure and dynamics at surfaces and interfaces
7. Design, fabrication, and applications of in situ fluid cell TEM to mineralization reactions
  Dongsheng Li, Michael H. Nielsen and James J. De Yoreo
8. X-ray Absorption Spectroscopy for the Structural Investigation of Self-Assembled-Monolayer-Directed Mineralization
  Jonathan R. I. Lee, Michael Bagge-Hansen, Trevor M. Willey, Robert W. Meulenberg, Michael H. Nielsen, Ich C. Tran and Tony van Buuren
9. Cryo-TEM Analysis of Collagen Fibrillar Stucture
  Bryan D. Quan and Eli D. Sone

Biomimetic crystallization techniques in vitro and in silico
10. Preparation of organothiol self-assembled monolayers for use in templated crystallization
  Michael H. Nielsen and Jonathan R.I. Lee
11. Experimental techniques for the growth and characterization of silica biomorphs and silica gardens
  Matthias Kellermeier, Fabian Glaab, Emilio Melero-García and Juan Manuel García-Ruiz
12. Precipitation in liposomes as a model for intracellular biomineralization
  Derk Joester
13. Polymer Mediated Growth of Crystals and Mesocrystals
  Helmut Coelfen
14. Phage display for the discovery of hydroxyapatite associated peptides
  Hyo-Eon Jin, Woo-Jae Chung and Seung-Wuk Lee

Protein structure, interactions and function
15. Quantitatively and Kinetically Identifying Binding Motifs of Amelogenin Proteins to Mineral Crystals through Biochemical and Spectroscopic Assays
  Li Zhu, Peter Hwang, H. Ewa Witkowska, Haichuan Liu and Wu Li
16. Using the RosettaSurface Algorithm to Predict Protein Structure at Mineral Surfaces
  Michael S. Pacella, Da Chen Emily Koo, Robin A. Thottungal and Jeffrey J. Gray
17. Investigating Protein Function in Biomineralized Tissues using Molecular Biology Techniques
  Christopher E. Killian and Fred H. Wilt

Mapping biomineral morphology and ultrastructure
18. Imaging the nanostructure of bone and dentin through small- and wide-angle scattering
  Silvia Pabisch, Wolfgang Wagermaier, Thomas Zander, Chenghao Li and Peter Fratzl
19. Synchrotron X-ray Nanomechanical Imaging of Mineralized Fibre Composites
  A. Karunaratne, N.J. Terrill and H. S. Gupta

Mapping mineral chemistry
20. Application of Total X-ray Scattering Methods and Pair Distribution Function Analysis for Study of Structure of Biominerals
  Richard J. Reeder and F. Marc Michel
21. X-ray Microdiffraction of Biominerals
  Nobumichi Tamura and P.U.P.A Gilbert
22. FT-IR and Raman studies of structure and bonding in mineral and organic-mineral composites
  Jinhui Tao
23. A mixed flow reactor method to synthesize amorphous calcium carbonate under controlled chemical conditions
  Christina R. Blue, J. Donald Rimstidt and Patricia M. Dove